Protein Name
Cyclic AMP-responsive element-binding protein 1
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
36633
Protein Length
341
Protein Domain
3D Structure
(PDB ID : 1kdx)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
-
Catalytic Site
Function
Phosphorylation-dependent transcription factor that stimulates transcription upon binding to the DNA cAMP response element (CRE), a sequence present in many viral and cellular promoters. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-117 phosphorylation. Involved in different cellular processes including the synchronization of circadian rhythmicity and the differentiation of adipose cells (By similarity).
Gene Ontology
GO:1990589; GO:0030424; GO:0000785; GO:0005759; GO:0005739; GO:0000790; GO:0005719; GO:0005654; GO:0005634; GO:0005667; GO:1990763; GO:0035497; GO:0001228; GO:0003700; GO:0000981; GO:0003690; GO:0035035; GO:0030544; GO:0042802; GO:0001102; GO:0000980; GO:0001225; GO:0043565; GO:0008134; GO:0044212; GO:0007568; GO:0007409; GO:0071398; GO:0035729; GO:1990314; GO:1990830; GO:1990090; GO:0036120; GO:0071300; GO:0071560; GO:0071294; GO:0034670; GO:0007623; GO:0007595; GO:0060430; GO:0007613; GO:0010629; GO:1901215; GO:0010944; GO:0021983; GO:0043065; GO:0055025; GO:0045600; GO:0046887; GO:0046889; GO:1900273; GO:0040018; GO:0045672; GO:0045899; GO:0045944; GO:0045893; GO:0032916; GO:0006468; GO:0050821; GO:0042981; GO:0008361; GO:0042752; GO:0048145; GO:0060251; GO:0014823; GO:0042493; GO:0033762; GO:0001666; GO:1902065; GO:0035094; GO:0033363; GO:0006366; GO:0007179; GO:0060509; GO:0008542