TNNI3 | Troponin I, cardiac muscle
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
TNNI3
Synonyms
TNNC1
Protein Name
Troponin I, cardiac muscle
UniProt ID
P19429 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000341838
NCBI Gene ID
7137
Molecular Weight
24008
Protein Length
210
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1j1d)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Function
Troponin I is the inhibitory subunit of troponin, the thin filament regulatory complex which confers calcium-sensitivity to striated muscle actomyosin ATPase activity.
Gene Ontology
GO:0097512; GO:1990584; GO:0005829; GO:0030017; GO:0005861; GO:0003779; GO:0051015; GO:0019855; GO:0048306; GO:0046872; GO:0019904; GO:0019901; GO:0030172; GO:0031014; GO:0060048; GO:0006874; GO:0060047; GO:0007507; GO:0006936; GO:0030049; GO:0032780; GO:0010882; GO:0006940; GO:0001980; GO:0003009; GO:0001570; GO:0055010
 
Gene Ontology