ITPKA | Inositol-trisphosphate 3-kinase A
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
ITPKA
Synonyms
-
Protein Name
Inositol-trisphosphate 3-kinase A
UniProt ID
P23677 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000260386
NCBI Gene ID
3706
Molecular Weight
51009
Protein Length
461
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1w2c)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
2.7.1.127; (BRENDA)
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
1D-myo-inositol 1,4,5-trisphosphate + ATP = 1D-myo-inositol 1,3,4,5-tetrakisphosphate + ADP + H(+)
Localization
Function
-
Gene Ontology
GO:0005829; GO:0043197; GO:0005524; GO:0005516; GO:0004683; GO:0008440; GO:0048365; GO:0030036; GO:0097062; GO:0006020; GO:0032958; GO:0043647; GO:0061003; GO:0048167; GO:0007165