PHKA1 | Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
PHKA1
Synonyms
PHKA
Protein Name
Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform
UniProt ID
P46020 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSP00000342469
NCBI Gene ID
5255
Molecular Weight
137312
Protein Length
1223
Protein Domain
InterPro | Pfam
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Cell membrane;
Function
Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. The alpha chain may bind calmodulin.
Gene Ontology
GO:0005829; GO:0005964; GO:0005886; GO:0005516; GO:0004689; GO:0006091; GO:0005977