Hist1h3a | Histone H3.1
 
image/svg+xmlExtracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion None Substrate Localization legend

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Sequence Viewer
Gene
Hist1h3a
Synonyms
H3a
Protein Name
Histone H3.1
UniProt ID
P68433 [go to UniProt ] [go to PDBe-KB ]
Ensembl Gene ID
ENSMUSP00000079670
NCBI Gene ID
31915231915336019897908
Molecular Weight
15404
Protein Length
136
Protein Domain
InterPro | Pfam
3D Structure
(PDB ID : 1guw)
PDBe | PDBj | RCSB PDB
DrugPort | ModBase | SwissModel
Target by Small Molecules
chEMBL
Protein-protein Interaction Database
STRING | IntAct | MINT
Gene Expression
Gene Expression Atlas | The Human Protein Atlas
Drugs and Diseases
Open Targets | OMIM
Enzyme Class
-
Catalytic Site
Catalytic Site Atlas
Catalytic Activity
-
Localization
Nucleus,Chromosome;
Function
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Gene Ontology
GO:0000228; GO:0000788; GO:0005654; GO:0000786; GO:0005634; GO:0032991; GO:0031492; GO:0046982; GO:0006335; GO:0006334; GO:0051290; GO:0060968