CaMKinet | Result

Gene

STX1A

Synonyms

STX1

Protein Name

Syntaxin-1A

UniProt ID

Q16623 [go to UniProt ] [go to PDBe-KB ]

Ensembl Gene ID

ENSP00000222812

NCBI Gene ID

6804

Molecular Weight

33023

Protein Length

288

Protein Domain

InterPro | Pfam

Target by Small Molecules

chEMBL

Protein-protein Interaction Database

STRING | IntAct | MINT

Gene Expression

Gene Expression Atlas | The Human Protein Atlas

Drugs and Diseases

Open Targets | OMIM

Enzyme Class

Catalytic Site

Catalytic Site Atlas

Catalytic Activity

Localization

Cytoplasmic vesicle,Secretory vesicle,Synaptic vesicle membrane,Cell junction,Synapse,Synaptosome,Cell membrane;Isoform 2: Secreted;

Function

Plays a role in hormone and neurotransmitter exocytosis (By similarity). Potentially involved in docking of synaptic vesicles at presynaptic active zones. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.

Gene Ontology

GO:0042641; GO:0030424; GO:0030054; GO:0005829; GO:0012505; GO:0005576; GO:0098978; GO:0016021; GO:0099056; GO:0030285; GO:0043005; GO:0031965; GO:0005886; GO:0014069; GO:0048787; GO:0042734; GO:0030141; GO:0031201; GO:0008021; GO:0070044; GO:0070032; GO:0070033; GO:0008076; GO:0043008; GO:0019855; GO:0048306; GO:0019869; GO:0044325; GO:0019900; GO:0032028; GO:0030674; GO:0019904; GO:0046982; GO:0047485; GO:0005484; GO:0000149; GO:0019221; GO:0006887; GO:0006886; GO:0045956; GO:0033605; GO:2000463; GO:0001956; GO:0010701; GO:0072657; GO:0050796; GO:0010807; GO:0009629; GO:0032940; GO:0035493; GO:0016081; GO:0031629; GO:0048278; GO:0006906