MDM2 | E3 ubiquitin-protein ligase Mdm2
 
 

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  • Double clicking on the substrate will redirect to the uniprot entry.
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  • Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
  • The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
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Graphics credits: Skylign

 
Gene Name Organism P-Site Sequence(+/-7) Conservation Disorder Curator Assessment Reliability Evidence Class Evidence Logic PubMed Phospho-ELM PhosphoSite-Plus
MAPKAPK2 (Q00987) Homo sapiens S157 SHLVSRPSTSSRRRA 0.615 0.6375 TP certain experimental 72 | 73 | 55 | 9 | 273 | 15688025 - In vitro
MAPKAPK2 (Q00987) Homo sapiens S166 SSRRRAISETEENSD 0.815 0.7718 TP certain experimental 72 | 73 | 55 | 9 | 273 | 15688025 - In vitro
PIM1 (Q00987) Homo sapiens S166 SSRRRAISETEENSD 0.815 0.7718 TP certain experimental 72 | 73 | 8 | 55 | 107 | 23 | 18467333 - In vitro and in vivo
PIM1* (Q00987) Homo sapiens S186 RQRKRHKSDSISLSF 0.958 0.6043 TP likely experimental 73 | 8 | 55 | 107 | 72 | 23 | 18467333 - In vitro and in vivo
DAPK1 (Q00987) Homo sapiens S166 SSRRRAISETEENSD 0.815 0.7718 TP certain - 161 | 131 | 9 | 73 | 15001356 - -
DAPK1 (Q00987) Homo sapiens S186 RQRKRHKSDSISLSF 0.958 0.6043 TP certain - 161 | 131 | 9 | 73 | 15001356 - -
PIM2* (Q00987) Homo sapiens S166 SSRRRAISETEENSD 0.815 0.7718 TP likely experimental 73 | 19166854 - -
PIM2* (Q00987) Homo sapiens S186 RQRKRHKSDSISLSF 0.958 0.6043 TP likely experimental 73 | 19166854 - -
DAPK3 (Q00987) Homo sapiens S186 RQRKRHKSDSISLSF 0.958 0.6043 - - - 73 | 161 | 15001356 - In vitro
RPS6KA1 (Q00987) Homo sapiens S166 SSRRRAISETEENSD 0.815 0.7718 - - - - - - -
RPS6KA1 (Q00987) Homo sapiens S186 RQRKRHKSDSISLSF 0.958 0.6043 - - - - - - -

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