Protein Name
Ribosomal protein S6 kinase alpha-6
UniProt ID
Ensembl Gene ID
NCBI Gene ID
Molecular Weight
83,872
Protein Length
745
Protein Domain
3D Structure
(PDB ID : N/A)
Target by Small Molecules
Protein-protein Interaction Database
Gene Expression
Drugs and Diseases
Enzyme Class
Catalytic Site
Catalytic Activity
ATP + a protein = ADP + a phosphoprotein.
Localization
Cytoplasm, cytosol Nucleus Note=Predominantly cytosolic.
Function
Constitutively active serine/threonine-protein kinase that exhibits growth-factor-independent kinase activity and that may participate in p53/TP53-dependent cell growth arrest signaling and play an inhibitory role during embryogenesis.
Gene Ontology
GO:0000287; GO:0001650; GO:0004672; GO:0004711; GO:0005524; GO:0005634; GO:0005654; GO:0005730; GO:0005739; GO:0005829; GO:0006978; GO:0007165; GO:0007417; GO:0016301; GO:0045992; GO:0070373; GO:2000381
