KEGG pathway - Progesterone-mediated oocyte maturation

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
RPS6KA1	Ribosomal protein S6 kinase alpha-1	Q15418	EEF2K \| MITF \| FOS \| ESR1 \| Nr4a1 \| ITGB4 \| CREB1 \| SLC9A1 \| FLNA \| EIF4B \| NFKBIA \| L1CAM \| IRS1 \| TSC2 \| Tsc2 \| GSK3B \| ETV1 \| DAPK1 \| RPS6 \| YBX1 \| CCT2 \| MDM2 \| MXD1 \| Mitf \| RPS6KA1 \| NFKBIB \| PPP1R3A \| Bad \| Kcnd3 \| Rps6ka1 \| Dlc1 \| Eif4b \| RPTOR \| DEPTOR \| ESR2 \| BAD \| CIC \| RANBP3 \| Krt17 \| METTL1 \| NDRG2 \| CARHSP1 \| Nos1 \| Cebpb \| CEBPB \| CDKN1B \| VASP \| GMFB \| Cebpb \| UBR5 \| Mapk7 \| MAPK7 \| WWC1 \| Gab2 \| CDC25C \| CHEK1 \| PDCD4 \| SOS1 \| LCP1 \| APAF1 \| Senp2 \| OSTF1 \| CDC25A \| EPHA2 \| CDC25B \| SLC9A3R1 \| CDC34 \| SENP2 \|
RPS6KA2	Ribosomal protein S6 kinase alpha-2	Q15349	FOS \| CREB1 \| ATF4 \| DAPK1 \| MEF2C \| Atf4 \| NFATC4 \| BAD \| RRN3 \| CDKN1B \| RPS6KA2 \|
RPS6KA3	Ribosomal protein S6 kinase alpha-3	P51812	KCNK3 \| ESR1 \| EIF2S1 \| Nr4a1 \| Htr2a \| Creb1 \| ATF4 \| EIF2AK2 \| Cebpb \| NFKBIA \| HIST1H2BB \| STAT3 \| Gata4 \| CDKN1B \| GSK3A \| GSK3B \| DAPK1 \| Mybpc3 \| RPS6 \| YBX1 \| PPP1R3A \| NFATC4 \| RRN3 \| HMGN1 \| TH \| TH \| TH \| CREB1 \| PFKFB2 \| Mybpc3 \| Rps6 \| HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J \| H3F3A; H3F3B \| PPP1R3A \| BAD \| CIC \| RANBP3 \| MAP3K5 \| WWC1 \| TH \| TINF2 \| LCP1 \| TBX21 \| FGFR1 \| STMN1 \| EPHA2 \| SLC9A3 \| CASP8 \|
RPS6KA6	Ribosomal protein S6 kinase alpha-6	Q9UK32

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
AKT1	RAC-alpha serine/threonine-protein kinase	P31749	MAPKAPK2 \| SIK2 \| PRKD1 \| CAMKK2 \|
CDC25A	M-phase inducer phosphatase 1	P30304	CHEK1 \| CHEK2 \| PIM1 \| RPS6KA1 \|
CDC25B	M-phase inducer phosphatase 2	P30305	MELK \| MAPKAPK2 \| BRSK1 \| CHEK1 \| RPS6KA1 \|
CDC25C	M-phase inducer phosphatase 3	P30307	Mark3 \| BRSK1 \| MARK3 \| CHEK1 \| CHEK2 \| MAPKAPK2 \| RPS6KA1 \|
CDC27	Cell division cycle protein 27 homolog	P30260
HSP90AA1	Heat shock protein HSP 90-alpha	P07900	PNCK \|
HSP90AB1	Heat shock protein HSP 90-beta	P08238	PNCK \|
PLK1	Serine/threonine-protein kinase PLK1	P53350	MAPKAPK2 \|
RPS6KA1	Ribosomal protein S6 kinase alpha-1	Q15418	RPS6KA1 \| MAPKAPK2 \|
CDC25B	M-phase inducer phosphatase 2	P30305	MELK \| MAPKAPK2 \| BRSK1 \| CHEK1 \| RPS6KA1 \|