| Gene |
EIF4G3
|
| Protein Name |
IF4G3_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Eukaryotic translation initiation factor 4 gamma 3 (eIF-4-gamma 3) (eIF-4G 3) (eIF4G 3) (eIF-4-gamma II) (eIF4GII) |
| Protein Family |
Eukaryotic initiation factor 4G family |
| NCBI Gene ID |
8672
|
| UniProt ID |
O43432
|
| Enzyme Class |
- |
| Molecular Weight |
176652 |
| Protein Length |
1585 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
N/A |
| Function (UniProt annotation) |
Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1. |
| Gene Ontology |
GO:0000339; GO:0003723; GO:0003729; GO:0003743; GO:0005829; GO:0006446; GO:0008135; GO:0016281 |
