| Gene |
CAMK2G
|
| Protein Name |
KCC2G_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
Calcium/calmodulin-dependent protein kinase type II subunit gamma (CaM kinase II subunit gamma) (CaMK-II subunit gamma) (EC 2.7.11.17) |
| Protein Family |
Protein kinase superfamily |
| NCBI Gene ID |
818
|
| UniProt ID |
Q13555
|
| Enzyme Class |
2.7.11.17 |
| Molecular Weight |
62607 |
| Protein Length |
558 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
ATP + a protein = ADP + a phosphoprotein. |
| Localization |
Sarcoplasmic reticulum membrane |
| Function (UniProt annotation) |
Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca(2+)/calmodulin-binding and autophosphorylation, and is involved in sarcoplasmic reticulum Ca(2+) transport in skeletal muscle and may function in dendritic spine and synapse formation and neuronal plasticity. In slow-twitch muscles, is involved in regulation of sarcoplasmic reticulum (SR) Ca(2+) transport and in fast-twitch muscle participates in the control of Ca(2+) release from the SR through phosphorylation of the ryanodine receptor-coupling factor triadin. In neurons, may participate in the promotion of dendritic spine and synapse formation and maintenance of synaptic plasticity which enables long-term potentiation (LTP) and hippocampus-dependent learning. |
| Gene Ontology |
GO:0000165; GO:0004674; GO:0004683; GO:0004723; GO:0005088; GO:0005516; GO:0005524; GO:0005654; GO:0005737; GO:0005829; GO:0005886; GO:0007399; GO:0014733; GO:0016020; GO:0030073; GO:0030154; GO:0030666; GO:0033017; GO:0042802; GO:0042803; GO:0043005; GO:0051259; GO:0051924; GO:0060333 |
