CaM Kinases known in this pathway:
| Name | Synonyms | EntryName | Phosphorylate Substrates |
|---|---|---|---|
| CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma | Q13555 | Bad | STAT3 | RELA | RARA | CAMK2G | DAB2 | OCLN | RRAD | BAD | | | TH | | RYR1 | STAT1 | GRIA1 | PEA15 | CREB1 | ATP2A2 | CEBPB | FLNA | CFL2 | DLG1 | ADCY3 | KRT18 | QDPR | GFAP | HSF1 | PLCB3 | KCND2 | SYN1 | ACACA | VIM | RYR2 | PPP3CA | GRIN2B | OPRM1 | PPP1R9B | VPS72 | PLN | | CAMK2A | |
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 | MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 | |
| CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma | Q13555 | CAMK2G | |
| CARD11 | Caspase recruitment domain-containing protein 11 | Q9BXL7 | CAMK2A | |
| ELK1 | ETS domain-containing protein Elk-1 | P19419 | RPS6KA5 | |
| ETS1 | Protein C-ets-1 | P14921 | CAMK2A | |
| FOS | Proto-oncogene c-Fos | P01100 | RPS6KA2 | RPS6KA1 | |
| IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta | O14920 | PRKAA2 | |
| JUN | Transcription factor AP-1 | P05412 | PRKD1 | |
| MAP4K1 | Mitogen-activated protein kinase kinase kinase kinase 1 | Q92918 | PRKD1 | |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEK1 | |
| NFKBIA | NF-kappa-B inhibitor alpha | P25963 | RPS6KA3 | RPS6KA1 | |
| NFKBIB | NF-kappa-B inhibitor beta | Q15653 | RPS6KA1 | |
| PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN | P60484 | STK11 | |
| RELA | Transcription factor p65 | Q04206 | PIM1 | CAMK2G | RPS6KA4 | RPS6KA5 | CAMK4 | CHEK1 | |
| SHC1 | SHC-transforming protein 1 | P29353 | Mapkapk2 | MAPKAPK2 | |
| SYK | Tyrosine-protein kinase SYK | P43405 | CHEK1 | PRKAA1 | PRKD1 | |