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| Parameter | Value |
|---|---|
| Gene | PPP2R5D |
| Protein Name | 2A5D_HUMAN |
| Organism | Homo sapiens (Human) |
| Alternative name(s) | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) |
| Protein Family | Phosphatase 2A regulatory subunit B56 family |
| NCBI Gene ID | 5528 |
| UniProt ID | Q14738 |
| Enzyme Class | - |
| Molecular Weight | 69992 |
| Protein Length | 602 |
| Protein Domain | InterPro | Pfam |
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
| Gene Expression | Gene Expression Atlas |
| Function and Disease | OMIM |
| Protein-protein Interaction Database | STRING | IntAct | MINT |
| Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
| Catalytic Activity (UniProt annotation) | - |
| Localization | Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis. |
| Function (UniProt annotation) | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
| Gene Ontology | GO:0000159; GO:0004721; GO:0004722; GO:0005634; GO:0005654; GO:0005829; GO:0006470; GO:0007165; GO:0007399; GO:0010801; GO:0019888; GO:0031952; GO:0035307; GO:0072542 |
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (O14757) | Homo sapiens | S60 | PSSNKRPSNSTPPPT | 0.24 | 0.9664 | - | - | - | - | - | - |
|
Reactome Pathways
KEGG Pathways
| Pathway ID | Pathway Name |
|---|---|
| hsa03015 | mRNA surveillance pathway |
| hsa04114 | Oocyte meiosis |
| hsa04310 | Wnt signaling pathway |
NCI Nature PID Pathways