Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | PPP2R5D |
Protein Name | 2A5D_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform (PP2A B subunit isoform B'-delta) (PP2A B subunit isoform B56-delta) (PP2A B subunit isoform PR61-delta) (PP2A B subunit isoform R5-delta) |
Protein Family | Phosphatase 2A regulatory subunit B56 family |
NCBI Gene ID | 5528 |
UniProt ID | Q14738 |
Enzyme Class | - |
Molecular Weight | 69992 |
Protein Length | 602 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cytoplasm. Nucleus. Note=Nuclear in interphase, nuclear during mitosis. |
Function (UniProt annotation) | The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. |
Gene Ontology | GO:0000159; GO:0004721; GO:0004722; GO:0005634; GO:0005654; GO:0005829; GO:0006470; GO:0007165; GO:0007399; GO:0010801; GO:0019888; GO:0031952; GO:0035307; GO:0072542 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CHEK1 (O14757) | Homo sapiens | S60 | PSSNKRPSNSTPPPT | 0.24 | 0.9664 | - | - | - | - | - | - |
|
Reactome Pathways
KEGG Pathways
Pathway ID | Pathway Name |
---|---|
hsa03015 | mRNA surveillance pathway |
hsa04114 | Oocyte meiosis |
hsa04310 | Wnt signaling pathway |
NCI Nature PID Pathways