Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PYGM (P00489) | Oryctolagus cuniculus | S15 | QEKRKQISVRGLAGV | - | 0.3529 | TP | certain | experimental | 8 | | 7706257 | - | - |
| MAPT * (P10636-8 ) | Homo sapiens | S237 | RTPPKSPSSAKSRLQ | 0.200 | 0.8894 | TP | certain | experimental | 72 | 107 | 132 | 135 | | 8999860 | - | - |
| MAPT * (P10636-8 ) | Homo sapiens | S262 | NVKSKIGSTENLKHQ | 0.606 | 0.8125 | TP | certain | experimental | 72 | 107 | 132 | 135 | | 8999860 | - | - |
| MAPT * (P10636-8 ) | Homo sapiens | S285 | INKKLDLSNVQSKCG | 0.404 | 0.5211 | TP | certain | experimental | 72 | 107 | 132 | 135 | | 8999860 | - | - |
| MAPT * (P10636-8 ) | Homo sapiens | S305 | KHVPGGGSVQIVYKP | 0.830 | 0.4901 | TP | certain | experimental | 72 | 107 | 132 | 135 | | 8999860 | - | - |
| MAPT (P10636-8) | Homo sapiens | S352 | DFKDRVQSKIGSLDN | 0.437 | 0.4619 | TP | certain | experimental | 72 | 107 | 132 | 135 | | 8999860 | - | - |
| Nrgn * (Q04940 ) | Rattus norvegicus | S36 | AAAKIQASFRGHMAR | - | 0.5139 | TP | certain | experimental | 132 | 72 | 135 | 16 | | 8454596 | - | - |
| Gap43 * (P07936 ) | Rattus norvegicus | S41 | AATKIQASFRGHITR | - | 0.662 | TP | certain | experimental | 132 | 72 | 135 | 16 | | 8454596 | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)