Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| MKNK2 (P08172) | Homo sapiens | S286 | EKESSNDSTSVSAVA | 0.892 | 0.7982 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S288 | ESSNDSTSVSAVASN | 0.990 | 0.805 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S283 | QGEEKESSNDSTSVS | 0.516 | 0.6482 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S234 | NQDPVSPSLVQGRIV | 0.936 | 0.5176 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S290 | SNDSTSVSAVASNMR | 0.990 | 0.7982 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S232 | VANQDPVSPSLVQGR | 0.709 | 0.4901 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S294 | TSVSAVASNMRDDEI | 0.615 | 0.7459 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S250 | PNNNNMPSSDDGLEH | 0.816 | 0.6482 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S251 | NNNNMPSSDDGLEHN | 0.679 | 0.7547 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S309 | TQDENTVSTSLGHSK | 0.402 | 0.7916 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S282 | VQGEEKESSNDSTSV | 0.604 | 0.6806 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | S311 | DENTVSTSLGHSKDE | 0.340 | 0.7672 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | T302 | NMRDDEITQDENTVS | 0.144 | 0.6948 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | T287 | KESSNDSTSVSAVAS | 0.994 | 0.7951 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | T271 | KAPRDPVTENCVQGE | 0.152 | 0.7951 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | T307 | EITQDENTVSTSLGH | 0.173 | 0.7916 | - | - | - | - | - | - | - |
| MKNK2 (P08172) | Homo sapiens | T310 | QDENTVSTSLGHSKD | 0.374 | 0.7843 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Kinase Gene Name" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)