Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CHEK1 (P30304) | Homo sapiens | T507 | KFRTKSRTWAGEKSK | 0.183 | 0.3948 | TP | certain | experimental | 72 | 73 | 140 | 55 | 8 | | 14559997 | - |
|
| CHEK1 (P30304) | Homo sapiens | S76 | SNLQRMGSSESTDSG | 0.668 | 0.5707 | TP | certain | experimental | 72 | 107 | 73 | 9 | | 12759351 | - | - |
| CHEK1 (P30304) | Homo sapiens | S124 | PALKRSHSDSLDHDI | 0.462 | 0.4476 | TP | certain | experimental | 72 | 107 | 9 | | 12759351 | - | - |
| CHEK1 (P30304) | Homo sapiens | S178 | LFTQRQNSAPARMLS | 0.959 | 0.6755 | TP | certain | experimental | 72 | 107 | 9 | | 12759351 | - | - |
| PIM1 (P30304) | Homo sapiens | S116 | PQKLLGCSPALKRSH | 0.618 | 0.5456 | - | - | - | - | - | Non high throughput (12411508) | - |
| CHEK2 (P30304) | Homo sapiens | S124 | PALKRSHSDSLDHDI | 0.462 | 0.4476 | - | - | - | - | - | Non high throughput (11298456) |
|
| CHEK1 (P30304) | Homo sapiens | S279 | VLKRPERSQEESPPG | 0.549 | 0.8872 | - | - | - | - | - | Non high throughput (12676583) |
|
| CHEK1 (P30304) | Homo sapiens | S293 | GSTKRRKSMSGASPK | 0.631 | 0.8713 | - | - | - | - | - | Non high throughput (12676583) |
|
| CHEK2 (P30304) | Homo sapiens | S178 | LFTQRQNSAPARMLS | 0.959 | 0.6755 | - | - | - | - | - | Non high throughput (12676583) |
|
| CHEK2 (P30304) | Homo sapiens | S279 | VLKRPERSQEESPPG | 0.549 | 0.8872 | - | - | - | - | - | Non high throughput (12676583) |
|
| CHEK2 (P30304) | Homo sapiens | S293 | GSTKRRKSMSGASPK | 0.631 | 0.8713 | - | - | - | - | - | Non high throughput (12676583) |
|
| CHEK1 (P30304) | Homo sapiens | S107 | NPMRRIHSLPQKLLG | 0.691 | 0.5382 | - | - | - | - | - | - | - |
| CHEK1 (P30304) | Homo sapiens | S298 | RKSMSGASPKESTNP | 0.371 | 0.8375 | - | - | - | - | - | - | - |
| CHEK2 (P30304) | Homo sapiens | S298 | RKSMSGASPKESTNP | 0.371 | 0.8375 | - | - | - | - | - | - | - |
| RPS6KA1 (P30304) | Homo sapiens | S295 | TKRRKSMSGASPKES | 0.296 | 0.8792 | - | - | - | - | - | - |
|
| RPS6KA1 (P30304) | Homo sapiens | S293 | GSTKRRKSMSGASPK | 0.631 | 0.8713 | - | - | - | - | - | - |
|
Help Instructions
- Hovering on the "*" in "Kinase Gene Name" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)