Graphics credits: COMPARTMENTS | More Info
Parameter | Value |
---|---|
Gene | SYN1 |
Protein Name | SYN1_HUMAN |
Organism | Homo sapiens (Human) |
Alternative name(s) | Synapsin-1 (Brain protein 4.1) (Synapsin I) |
Protein Family | Synapsin family |
NCBI Gene ID | 6853 |
UniProt ID | P17600 |
Enzyme Class | - |
Molecular Weight | 74111 |
Protein Length | 705 |
Protein Domain | InterPro | Pfam |
3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase | SwissModel |
Gene Expression | Gene Expression Atlas |
Function and Disease | OMIM |
Protein-protein Interaction Database | STRING | IntAct | MINT |
Kinase Database | Phospho.ELM | PhosphoSite | NetworKIN |
Catalytic Activity (UniProt annotation) | - |
Localization | Cell junction, synapse. Golgi apparatus |
Function (UniProt annotation) | Neuronal phosphoprotein that coats synaptic vesicles, binds to the cytoskeleton, and is believed to function in the regulation of neurotransmitter release. The complex formed with NOS1 and CAPON proteins is necessary for specific nitric-oxid functions at a presynaptic level. |
Gene Ontology | GO:0000795; GO:0003779; GO:0005215; GO:0005524; GO:0005794; GO:0005829; GO:0005856; GO:0007268; GO:0007269; GO:0008021; GO:0014069; GO:0019901; GO:0030054; GO:0030424; GO:0030425; GO:0030672; GO:0043209; GO:0046928; GO:0048306; GO:0048666; GO:0048786; GO:0050808; GO:0097091; GO:0098685; GO:0098850; GO:0098993; GO:2000300 |
Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
---|---|---|---|---|---|---|---|---|---|---|---|---|
CAMK1 (Q14012) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.562 | - | - | - | - | - | - |
|
CAMK2A (Q9UQM7) | Homo sapiens | S605 | AGPTRQASQAGPVPR | 0.334 | 0.9909 | - | - | - | - | - | - |
|
CAMK2B (Q13554) | Homo sapiens | S605 | AGPTRQASQAGPVPR | 0.334 | 0.9909 | - | - | - | - | - | - |
|
CAMK2D (Q13557) | Homo sapiens | S605 | AGPTRQASQAGPVPR | 0.334 | 0.9909 | - | - | - | - | - | - |
|
CAMK2G (Q13555) | Homo sapiens | S605 | AGPTRQASQAGPVPR | 0.334 | 0.9909 | - | - | - | - | - | - |
|
CAMK4 (Q16566) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.562 | - | - | - | - | - | - |
|
CAMK1D (Q8IU85) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.562 | - | - | - | - | - | - |
|
CAMK1G (Q96NX5) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.562 | - | - | - | - | - | - |
|
CAMK2A (Q9UQM7) | Homo sapiens | S568 | PQATRQTSVSGPAPP | 0.924 | 0.9903 | - | - | - | - | - | - |
|
CAMK2B (Q13554) | Homo sapiens | S568 | PQATRQTSVSGPAPP | 0.924 | 0.9903 | - | - | - | - | - | - |
|
CAMK2D (Q13557) | Homo sapiens | S568 | PQATRQTSVSGPAPP | 0.924 | 0.9903 | - | - | - | - | - | - |
|
CAMK2G (Q13555) | Homo sapiens | S568 | PQATRQTSVSGPAPP | 0.924 | 0.9903 | - | - | - | - | - | - |
|
Reactome Pathways
No KEGG pathways found
No NCI Nature pathways found