CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	MYL12A
Protein Name	ML12A_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Myosin regulatory light chain 12A (Epididymis secretory protein Li 24) (HEL-S-24) (MLC-2B) (Myosin RLC) (Myosin regulatory light chain 2, nonsarcomeric) (Myosin regulatory light chain MRLC3)
Protein Family	N/A
NCBI Gene ID	10627
UniProt ID	P19105
Enzyme Class	-
Molecular Weight	19794
Protein Length	171
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion (By similarity).
Gene Ontology	GO:0005509; GO:0005829; GO:0006936; GO:0016459; GO:0070062; GO:0070527

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
MYLK2 (Q9H1R3)	Homo sapiens	S19	KRPQRATSNVFAMFD	0.788	0.5665	TP	certain	experimental	62 \| 72 \| 74 \|	11942626	-	-
MYLK2 (Q9H1R3)	Homo sapiens	T18	KKRPQRATSNVFAMF	0.591	0.5456	TP	certain	experimental	62 \| 72 \| 74 \|	11942626	-	-
CAMK1 (Q14012)	Homo sapiens	S19	KRPQRATSNVFAMFD	0.788	0.5665	-	-	-	-	-	-	-
CAMK4 (Q16566)	Homo sapiens	S19	KRPQRATSNVFAMFD	0.788	0.5665	-	-	-	-	-	-	-
DAPK1 (P53355)	Homo sapiens	S19	KRPQRATSNVFAMFD	0.788	0.5665	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04510	Focal adhesion
hsa04530	Tight junction
hsa04670	Leukocyte transendothelial migration
hsa04810	Regulation of actin cytoskeleton

No NCI Nature pathways found