CaM Kinases known in this pathway:
| Name | Synonyms | EntryName | Phosphorylate Substrates |
|---|---|---|---|
| MYLK | Myosin light chain kinase, smooth muscle | Q15746 | MYL12B | CALD1 | Myl12b | MYL2 | CALD1 | MYLK | CALD1 | |
| MYLK2 | Myosin light chain kinase 2, skeletal/cardiac muscle | Q9H1R3 | MYL9 | MYL12A | MYL12B | MEF2C | |
| MYLK3 | Myosin light chain kinase 3 | Q32MK0 | Ppp1r2 | PPP1R2B | |
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| ARPC5 | Actin-related protein 2/3 complex subunit 5 | O15511 | MAPKAPK2 | |
| BAIAP2 | Brain-specific angiogenesis inhibitor 1-associated protein 2 | Q9UQB8 | MARK2 | |
| CFL1 | Cofilin-1 | P23528 | PRKD1 | HUNK | |
| EGFR | Epidermal growth factor receptor | P00533 | PRKD1 | CAMK2A | PRKAA1 | |
| ITGB1 | Integrin beta-1 | P05556 | CAMK2A | |
| ITGB4 | Integrin beta-4 | P16144 | RPS6KA1 | |
| LIMK1 | LIM domain kinase 1 | P53667 | MAPKAPK2 | CAMK4 | |
| MYL12A | Myosin regulatory light chain 12A | P19105 | MYLK2 | CAMK1 | CAMK4 | DAPK1 | |
| MYL12B | Myosin regulatory light chain 12B | O14950 | MYLK | Dapk1 | MYLK2 | DAPK3 | DAPK1 | |
| MYL9 | Myosin regulatory light polypeptide 9 | P24844 | Camk1 | MYLK2 | DAPK3 | CAMK1 | DAPK1 | DAPK2 | |
| PAK1 | Serine/threonine-protein kinase PAK 1 | Q13153 | BRSK2 | STK11 | |
| PAK2 | Serine/threonine-protein kinase PAK 2 | Q13177 | |
| PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha | P48426 | PRKD1 | |
| PPP1R12A | Protein phosphatase 1 regulatory subunit 12A | O14974 | NUAK1 | DAPK3 | |
| SLC9A1 | Sodium/hydrogen exchanger 1 | P19634 | RPS6KA1 | |
| SSH1 | Protein phosphatase Slingshot homolog 1 | Q8WYL5 | PRKD2 | PRKD1 | CAMK2D | |