CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	ACACA
Protein Name	ACACA_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Acetyl-CoA carboxylase 1 (ACC1) (EC 6.4.1.2) (ACC-alpha) [Includes: Biotin carboxylase (EC 6.3.4.14)]
Protein Family	N/A
NCBI Gene ID	31
UniProt ID	Q13085
Enzyme Class	6.4.1.2; 6.3.4.14
Molecular Weight	265554
Protein Length	2346
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	ATP + acetyl-CoA + HCO(3)(-) = ADP + phosphate + malonyl-CoA.
Localization	Cytoplasm.
Function (UniProt annotation)	Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.
Gene Ontology	GO:0001650; GO:0001894; GO:0003989; GO:0004075; GO:0005524; GO:0005829; GO:0006084; GO:0006633; GO:0006853; GO:0015629; GO:0019538; GO:0031325; GO:0042802; GO:0045540; GO:0046872; GO:0046949; GO:0051289; GO:0055088; GO:0071380; GO:2001295

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
PRKAA2 (P54646)	Homo sapiens	S80	LHIRSSMSGLHLVKQ	0.956	0.2918	-	-	-	-	-	-	In vivo
PRKAA2 (P54646)	Homo sapiens	S78	LALHIRSSMSGLHLV	0.987	0.3019	-	-	-	-	-	-	-
PRKAA1 (Q13131)	Homo sapiens	S1201	IPTLNRMSFSSNLNH	0.142	0.2849	-	-	-	-	-	-	-
CAMK4 (Q16566)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK1D (Q8IU85)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK1G (Q96NX5)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK2A (Q9UQM7)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK2B (Q13554)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK2D (Q13557)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-
CAMK2G (Q13555)	Homo sapiens	S25	RFIIGSVSEDNSEDE	0	0.4979	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

No NCI Nature pathways found