Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LATS1 * (O95835 ) | Homo sapiens | S464 | NIPVRSNSFNNPLGN | 0.913 | 0.712 | TP | certain | experimental | 23 | 9 | 55 | | 19927127 | - | - |
| PPP1R12A (O14974) | Homo sapiens | S445 | LGLRKTGSYGALAEI | 0.674 | 0.494 | TP | certain | experimental | 135 | 30 | 9 | | 20354225 | - | - |
| PPP1R12A (O14974) | Homo sapiens | S472 | AGVTRSASSPRLSSS | 0.669 | 0.7289 | TP | certain | experimental | 135 | 30 | 9 | | 20354225 | - | - |
| PPP1R12A (O14974) | Homo sapiens | S910 | SLLGRSGSYSYLEER | 0.140 | 0.4979 | TP | likely | experimental | 135 | 30 | 9 | | 20354225 | - | - |
| CASP6 (P55212) | Homo sapiens | S257 | TLVNRKVSQRRVDFC | 0.720 | 0.1731 | TP | certain | experimental | 72 | 30 | 8 | | 22483120 | - | - |
| TP53 * (P04637 ) | Homo sapiens | S15 | PSVEPPLSQETFSDL | 0.830 | 0.708 | TP | certain | experimental | 23 | 72 | 55 | 73 | 9 | | 21317932 | - | - |
| TP53 * (P04637 ) | Homo sapiens | S392 | FKTEGPDSD______ | 0.808 | 0.7672 | TP | certain | experimental | 23 | 72 | 55 | 73 | 9 | | 21317932 | - | - |
| MAPT (P10636-8) | Homo sapiens | S356 | RVQSKIGSLDNITHV | 0.096 | 0.4831 | - | - | - | - | - | - |
|
| MAPT (P10636-8) | Homo sapiens | S262 | NVKSKIGSTENLKHQ | 0.606 | 0.8125 | - | - | - | - | - | - |
|
| CDKN1A (P38936) | Homo sapiens | S146 | GRKRRQTSMTDFYHS | 0.575 | 0.7163 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)