Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PFKFB2 (O60825) | Homo sapiens | S466 | PVRMRRNSFTPLSSS | 0.089 | 0.5807 | TP | certain | experimental | 214 | 133 | 8 | 73 | 55 | | 11069105 | - |
|
| HNF4A (P41235) | Homo sapiens | S313 | GKIKRLRSQVQVSLE | 0.060 | 0.2364 | TP | certain | experimental | 72 | 73 | 8 | 205 | | 12740371 | - |
|
| Lipe (P15304-2) | Rattus norvegicus | S565 | ESMRRSVSEAALAQP | - | 0.5807 | TP | certain | experimental | 55 | | 15033481 | - | - |
| NOS3 (P29474) | Homo sapiens | S1177 | TSRIRTQSFSLQERQ | 0.140 | 0.433 | TP | certain | experimental | 30 | 55 | 23 | 135 | | 10025949 | - | - |
| MDM4 (O15151) | Homo sapiens | S342 | SKLTHSLSTSDITAI | 0.727 | 0.4292 | TP | certain | experimental | 72 | 73 | 9 | 30 | 55 | | 24190973 | - | - |
| NOS3 (P29474) | Homo sapiens | T495 | TGITRKKTFKEVANA | 0.231 | 0.3019 | TP | certain | experimental | 30 | 55 | 23 | 135 | | 10025949 | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)