Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CREM * (Q03060-2 ) | Homo sapiens | S87 | EILSRRPSYRKILNE | 0.756 | 0.5382 | TP | certain | experimental | 72 | 9 | 74 | | 11050006 | - | - |
| CREB1 (P16220) | Homo sapiens | S133 | EILSRRPSYRKILND | - | 0.4979 | TP | certain | experimental | 9 | 72 | | 11050006 | - | - |
| CREM (Q03060-1) | Homo sapiens | S118 | ETDESAESEGVIDSH | 0.638 | 0.7595 | TP | certain | experimental | 72 | 9 | 74 | | 11050006 | - | - |
| NUMB (P49757-9) | Homo sapiens | S22 | EQLARQGSFRGFPAL | 0.728 | 0.5139 | - | - | - | - | - | - | - |
| EP300 (Q09472) | Homo sapiens | S89 | SELLRSGSSPNLNMG | 0.391 | 0.6851 | - | - | - | - | - | - | - |
| ACACA (Q13085) | Homo sapiens | S25 | RFIIGSVSEDNSEDE | 0.000 | 0.4901 | - | - | - | - | - | - | - |
| SYN1 (P17600) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.5533 | - | - | - | - | - | - | - |
| CAMK1 (Q14012) | Homo sapiens | T177 | DPGSVLSTACGTPGY | 0.726 | 0.3215 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)