Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Gene Name | Organism | P-Site | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| RPS6KA3 (P53355) | Homo sapiens | S289 | QALSRKASAVNMEKF | - | 0.3356 | TP | certain | experimental | 72 | 73 | 140 | 214 | 9 | 55 | | 16213824 | - |
|
| DAPK1 (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | TP | certain | - | 9 | 72 | 73 | | 11579085 | - | - |
| DAPK1* (P53355) | Homo sapiens | S313 | KQSVRLISLCQRLSR | - | 0.0888 | TP | likely | - | 73 | 8 | | 11579085 | - | - |
| DAPK2 (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | - | - | - | - | - | - | - |
| DAPK3 (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | - | - | - | - | - | - | - |
| RPS6KA2 (P53355) | Homo sapiens | S289 | QALSRKASAVNMEKF | - | 0.3356 | - | - | - | - | - | Non high throughput (16213824) | - |
| RPS6KA1 (P53355) | Homo sapiens | S289 | QALSRKASAVNMEKF | - | 0.3356 | - | - | - | - | - | - |
|
| STK17A (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | - | - | - | - | - | - | - |
| STK17B (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Kinase Gene Name" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)