| Gene |
ELK1
|
| Protein Name |
ELK1_HUMAN |
| Organism |
Homo sapiens (Human) |
| Alternative name(s) |
ETS domain-containing protein Elk-1 |
| Protein Family |
ETS family |
| NCBI Gene ID |
2002
|
| UniProt ID |
P19419
|
| Enzyme Class |
- |
| Molecular Weight |
44888 |
| Protein Length |
428 |
| Protein Domain |
InterPro |
Pfam
|
| 3D Structure |
PDBe |
PDBj |
RCSB PDB |
DrugPort
ModBase |
SwissModel
|
| Gene Expression |
Gene Expression Atlas
|
| Function and Disease |
OMIM |
| Protein-protein Interaction Database |
STRING |
IntAct |
MINT
|
| Kinase Database |
Phospho.ELM
|
PhosphoSite
| NetworKIN
|
| Catalytic Activity (UniProt annotation) |
- |
| Localization |
Nucleus. |
| Function (UniProt annotation) |
Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity). |
| Gene Ontology |
GO:0000978; GO:0000981; GO:0001077; GO:0001085; GO:0003682; GO:0003700; GO:0005634; GO:0005654; GO:0005739; GO:0006357; GO:0009416; GO:0030154; GO:0030425; GO:0043025; GO:0043679; GO:0045893; GO:0045944; GO:0071394; GO:0071480; GO:0071774; GO:1901216 |
