Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| CDK16 (Q00536) | Homo sapiens | S12 | KKIKRQLSMTLRGGR | 0.998 | 0.7163 | TP | certain | experimental | 66 | 40 | 23 | 72 | 9 | | 22798068 | - | - |
| PAK1 (Q13153) | Homo sapiens | T423 | PEQSKRSTMVGTPYW | 0.735 | 0.4149 | TP | certain | experimental | 23 | 72 | 73 | 36 | | 22669945 | - | - |
| PRKAA1 (Q13131) | Homo sapiens | T183 | SDGEFLRTSCGSPNY | 0.698 | 0.2884 | - | - | - | - | - | - |
|
| TSC2 (P49815) | Homo sapiens | S1387 | QPLSKSSSSPELQTL | 0.645 | 0.8462 | - | - | - | - | - | - |
|
| MAPT (P10636) | Homo sapiens | S579 | NVKSKIGSTENLKHQ | 0.790 | 0.8125 | - | - | - | - | - | - | - |
| WEE1 (P30291) | Homo sapiens | S642 | KKMNRSVSLTIY___ | 0.904 | 0.1759 | - | - | - | - | - | - | - |
| (B4DX61) | Homo sapiens | S233 | SGLYRSPSMPENLNR | - | 0.6136 | - | - | - | - | - | - | - |
| MAPT (P10636) | Homo sapiens | T529 | TPGSRSRTPSLPTPP | 0.375 | 0.9725 | - | - | - | - | - | - | - |
| BRSK2 (Q8IWQ3) | Homo sapiens | T174 | VGDSLLETSCGSPHY | 0.628 | 0.1671 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)