CaMKinet | Result

Sequence Viewer

Parameter	Value
Gene	MYL9
Protein Name	MYL9_HUMAN
Organism	Homo sapiens (Human)
Alternative name(s)	Myosin regulatory light polypeptide 9 (20 kDa myosin light chain) (LC20) (MLC-2C) (Myosin RLC) (Myosin regulatory light chain 2, smooth muscle isoform) (Myosin regulatory light chain 9) (Myosin regulatory light chain MRLC1)
Protein Family	N/A
NCBI Gene ID	10398
UniProt ID	P24844
Enzyme Class	-
Molecular Weight	19827
Protein Length	172
Protein Domain	InterPro \| Pfam
3D Structure	PDBe \| PDBj \| RCSB PDB \| DrugPort ModBase \| SwissModel
Gene Expression	Gene Expression Atlas
Function and Disease	OMIM
Protein-protein Interaction Database	STRING \| IntAct \| MINT
Kinase Database	Phospho.ELM \| PhosphoSite \| NetworKIN
Catalytic Activity (UniProt annotation)	-
Localization	N/A
Function (UniProt annotation)	Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
Gene Ontology	GO:0001725; GO:0005509; GO:0005829; GO:0005859; GO:0006936; GO:0006937; GO:0008307; GO:0030018; GO:0032036; GO:0045652; GO:0070527

Gene Ontology

Gene Name	Organism	P-Site	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
Camk1 (Q63450)	Rattus norvegicus	S20	KRPQRATSNVFAMFD	0.877	0.5665	TP	certain	experimental	72 \| 73 \| 55 \| 8 \|	12081505	-	In vivo
MYLK2 (Q9H1R3)	Homo sapiens	S20	KRPQRATSNVFAMFD	0.877	0.5665	TP	certain	experimental	62 \| 72 \| 74 \|	11942626	-	-
DAPK3 (O43293)	Homo sapiens	S20	KRPQRATSNVFAMFD	0.877	0.5665	TP	certain	-	55 \| 74 \|	17087515	-	-
MYLK2 (Q9H1R3)	Homo sapiens	T19	KKRPQRATSNVFAMF	0.572	0.5342	TP	certain	experimental	62 \| 72 \| 74 \|	11942626	-	-
CAMK1 (Q14012)	Homo sapiens	S20	KRPQRATSNVFAMFD	0.877	0.5665	-	-	-	-	-	-	In vivo
DAPK3 (O43293)	Homo sapiens	T19	KKRPQRATSNVFAMF	0.572	0.5342	-	-	-	-	15096528	Non high throughput (15096528)	-
DAPK1 (P53355)	Homo sapiens	S20	KRPQRATSNVFAMFD	0.877	0.5665	-	-	-	-	-	-	-
DAPK2 (Q9UIK4)	Homo sapiens	S20	KRPQRATSNVFAMFD	0.877	0.5665	-	-	-	-	-	-	-

Reactome Pathways

Pathway ID	Pathway Name
R-HSA-1280215	Cytokine Signaling in Immune system \| Reactome Pathway
R-HSA-168256	Immune System \| Reactome Pathway
R-HSA-449147	Signaling by Interleukins \| Reactome Pathway
R-HSA-6785807	Interleukin-4 and Interleukin-13 signaling \| Reactome Pathway

KEGG Pathways

Pathway ID	Pathway Name
hsa04270	Vascular smooth muscle contraction
hsa04510	Focal adhesion
hsa04530	Tight junction
hsa04670	Leukocyte transendothelial migration
hsa04810	Regulation of actin cytoskeleton

No NCI Nature pathways found