Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BAD (Q92934) | Homo sapiens | S75 | EIRSRHSSYPAGTED | 0.509 | 0.8198 | - | - | - | - | - | Non high throughput (10558990) | - |
| CREB1 (P16220) | Homo sapiens | S133 | EILSRRPSYRKILND | - | 0.4979 | - | - | - | - | - | Non high throughput (11698596) |
|
| RRN3 (Q9NYV6) | Homo sapiens | S649 | PVLYMQPSPL_____ | 0.500 | 0.4831 | - | - | - | - | - | Non high throughput (12620228) | - |
| CDKN1B (P46527) | Homo sapiens | T198 | PGLRRRQT_______ | 0.507 | 0.9488 | - | - | - | - | - | Non high throughput (14504289) | - |
| ATF4 (P18848) | Homo sapiens | S245 | TRGSPNRSLPSPGVL | 0.283 | 0.7547 | - | - | - | - | - | Non high throughput (15109498) | - |
| Atf4 (Q06507) | Mus musculus | S251 | NLPSPGGSRGSPRPK | - | 0.9362 | - | - | - | - | - | Non high throughput (15109498) | - |
| NFATC4 (Q14934) | Homo sapiens | S676 | SNGRRKRSPTQSFRF | 0.769 | 0.3286 | - | - | - | - | - | Non high throughput (15657420) | - |
| DAPK1 (P53355) | Homo sapiens | S289 | QALSRKASAVNMEKF | - | 0.3356 | - | - | - | - | - | Non high throughput (16213824) | - |
| MEF2C (Q06413) | Homo sapiens | S192 | GVTHRPPSAGNTGGL | 0.696 | 0.8565 | - | - | - | - | - | Non high throughput (17630987) | - |
| FOS (P01100) | Homo sapiens | S362 | AAAHRKGSSSNEPSS | 0.803 | 0.5758 | - | - | - | - | - | Non high throughput (11585927, 9920881) | - |
| RPS6KA2 (Q15349) | Homo sapiens | S218 | DHDKRAYSFCGTIEY | 0.780 | 0.1137 | - | - | - | - | - | - |
|
| RPS6KA2 (Q15349) | Homo sapiens | T570 | AGNGLLMTPCYTANF | 0.752 | 0.1206 | - | - | - | - | - | - |
|
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)