CaMKinet | Result

Help Instruction

Double clicking on the substrate will redirect to the uniprot entry.
Clicking in the block having the substrate will zoom into its phophosites
Clicking the center of the circle will lead to zooming out.
Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
Clicking in the top right corner on the camara icon will download the image.

Sequence Logo

Graphics credits: Skylign

Substrate	Organism	PSite	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
TP53 (P04637)	Homo sapiens	S392	FKTEGPDSD______	0.808	0.7672	TP	certain	not annotated	74 \| 8 \| 72 \| 73 \| 55 \|	17108107	-	In vitro and in vivo
TP53 (P04637)	Homo sapiens	S15	PSVEPPLSQETFSDL	0.830	0.708	TP	certain	experimental	74 \| 8 \| 72 \| 73 \| 55 \|	17108107	-	In vitro and in vivo
MBP (P25274)	Oryctolagus cuniculus	T65	KDHAARTTHYGSLPQ	-	0.8198	U	likely	experimental	135 \| 273 \| 73 \|	12805220	-	In vitro
Prkaa1 * (P54645 )	Rattus norvegicus	T183	SDGEFLRTSCGSPNY	-	0.2884	TP	likely	experimental	73 \| 55 \|	14614828	-	In vitro
MELK (Q14680)	Homo sapiens	T167	NKDYHLQTCCGSLAY	0.843	0.1424	TP	certain	experimental	214 \| 8 \|	14976552	Non high throughput (14976552)	In vitro
STK11 (Q15831)	Homo sapiens	T189	LLLTTGGTLKISDLG	0.486	0.2129	TP	certain	experimental	73 \| 8 \|	11430832	Non high throughput (11430832)	In vitro
BRSK1 (Q8TDC3-2)	Homo sapiens	T205	VGDSLLETSCGSPHY	0.678	0.1702	TP	certain	experimental	214 \| 8 \|	14976552	Non high throughput (14976552)	In vitro
PTEN (P60484)	Homo sapiens	S380	EPDHYRYSDTTDSDP	0.594	0.8966	U	likely	experimental	72 \| 9 \| 55 \|	15987703	-	-
PTEN (P60484)	Homo sapiens	S385	RYSDTTDSDPENEPF	0.894	0.8279	U	likely	experimental	72 \| 9 \| 55 \|	15987703	-	-
MARK3 (P27448)	Homo sapiens	S215	KLDTFCGSPPYAAPE	0.605	0.1643	TP	certain	experimental	9 \| 55 \| 30 \| 133 \| 135 \| 72 \| 73 \|	14976552	-	-
PTEN (P60484)	Homo sapiens	T382	DHYRYSDTTDSDPEN	0.540	0.8493	U	likely	experimental	72 \| 9 \| 55 \|	15987703	-	-
PRKAA2 (P54646)	Homo sapiens	T172	SDGEFLRTSCGSPNY	0.703	0.2715	TP	certain	experimental	72 \| 55 \| 73 \| 23 \|	14985505	-	-
PTEN (P60484)	Homo sapiens	T383	HYRYSDTTDSDPENE	0.261	0.8493	U	likely	experimental	72 \| 9 \| 55 \|	15987703	-	-
SNRK (Q9NRH2)	Homo sapiens	T173	QPGKKLTTSCGSLAY	0.690	0.2817	TP	certain	experimental	8 \| 135 \| 30 \| 72 \|	15733851	-	-
STK11 (Q15831)	Homo sapiens	T185	KPGNLLLTTGGTLKI	0.389	0.2129	TP	certain	experimental	30 \| 72 \| 133 \| 135 \|	12805220	-	-
STK11 (Q15831)	Homo sapiens	T402	TEAAQLSTKSRAEGR	0.175	0.8198	TP	certain	experimental	30 \| 72 \| 133 \| 135 \|	12805220	-	-
STK11 (Q15831)	Homo sapiens	T336	KDRWRSMTVVPYLED	0.974	0.4541	TP	certain	experimental	72 \| 55 \| 30 \| 133 \| 135 \|	12805220	-	-
STK11 (Q15831)	Homo sapiens	T363	IEDDIIYTQDFTVPG	0.391	0.346	TP	certain	experimental	72 \| 55 \| 30 \| 133 \| 135 \|	12805220	-	-
BRSK1 (Q8TDC3)	Homo sapiens	T189	VGDSLLETSCGSPHY	0.685	0.1702	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
BRSK2 (Q8IWQ3)	Homo sapiens	T174	VGDSLLETSCGSPHY	0.628	0.1671	TP	certain	experimental	9 \| 55 \| 30 \| 135 \| 72 \| 73 \|	14976552	-	-
MARK1 (Q9P0L2)	Homo sapiens	T215	TVGNKLDTFCGSPPY	0.700	0.2503	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
MARK2 (Q7KZI7)	Homo sapiens	T208	TFGNKLDTFCGSPPY	0.633	0.1969	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
MARK3 (P27448)	Homo sapiens	T211	TVGGKLDTFCGSPPY	0.642	0.2399	TP	certain	experimental	9 \| 55 \| 30 \| 133 \| 135 \| 72 \| 73 \|	14976552	-	-
MARK4 (Q96L34)	Homo sapiens	T214	TLGSKLDTFCGSPPY	0.759	0.1969	TP	certain	experimental	9 \| 55 \| 30 \| 133 \| 135 \| 72 \| 73 \|	14976552	-	-
NUAK2 (Q9H093)	Homo sapiens	T208	HQGKFLQTFCGSPLY	0.754	0.087	TP	certain	experimental	9 \| 55 \| 30 \| 133 \| 135 \| 72 \| 73 \|	14976552	-	-
NUAK1 (O60285)	Homo sapiens	T211	QKDKFLQTFCGSPLY	0.765	0.0967	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
SIK1 (P57059)	Homo sapiens	T182	KSGEPLSTWCGSPPY	0.694	0.2094	TP	certain	experimental	9 \| 55 \| 30 \| 133 \| 135 \| 72 \| 73 \|	14976552	-	-
SIK2 (Q9H0K1)	Homo sapiens	T175	KSGELLATWCGSPPY	0.707	0.0749	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
STRADA (Q7RTN6)	Homo sapiens	T329	GLSDSLTTSTPRPSN	0.110	0.7982	TP	certain	experimental	23 \| 72 \| 73 \| 30 \| 133 \| 135 \| 9 \|	12805220	-	-
STRADA (Q7RTN6)	Homo sapiens	T419	SGIFGLVTNLEELEV	0.145	0.3392	TP	certain	experimental	23 \| 72 \| 73 \| 30 \| 133 \| 135 \| 9 \|	12805220	-	-
SMAD4 (Q13485)	Homo sapiens	T77	KCVTIQRTLDGRLQV	0.728	0.3566	TP	certain	experimental	72 \| 135 \| 62 \|	20974850	-	-
PAK1 (Q13153)	Homo sapiens	T109	QWARLLQTSNITKSE	0.052	0.6806	TP	certain	experimental	72 \| 73 \| 9 \| 30 \|	20400510	-	-
SIK3 (J3KPC8)	Homo sapiens	T221	TPGQLLKTWCGSPPY	0.456	0.1137	TP	certain	experimental	9 \| 55 \| 72 \| 73 \|	14976552	-	-
Stk11 (Q9WTK7)	Mus musculus	T336	KDRWRSMTVVPYLED	-	0.433	-	-	-	-	-	Non high throughput (11853558)	-
Stk11 (Q9WTK7)	Mus musculus	T366	IEDGIIYTQDFTVPG	-	0.2224	-	-	-	-	-	Non high throughput (11853558)	-
SIK3 (Q9Y2K2)	Homo sapiens	T221	TPGQLLKTWCGSPPY	0.456	0.1137	-	-	-	-	-	Non high throughput (14976552)	-
MARK3 (P27448-2)	Homo sapiens	T234	TVGGKLDTFCGSPPY	0.499	0.2258	-	-	-	-	-	Non high throughput (14976552)	-
STK11 (Q15831)	Homo sapiens	S428	SSKIRRLSACKQQ__	0.975	0.3774	-	-	-	-	-	-	In vitro
Sik1 (Q9R1U5)	Rattus norvegicus	T182	KPGEPLSTWCGSPPY	-	0.2609	-	-	-	-	-	-	In vivo
ETV4 (P43268)	Homo sapiens	S396	AMNYDKLSRSLRYYY	0.612	0.2258	-	-	-	-	-	-	-
GSK3B (P49841)	Homo sapiens	S9	SGRPRTTSFAESCKP	0.500	0.5951	-	-	-	-	-	-	-
PRKAA2 (P54646)	Homo sapiens	T485	EQRSGSSTPQRSCSA	0.154	0.5176	-	-	-	-	-	-	-
SIK1B (A0A0B4J2F2)	Homo sapiens	T182	KSGEPLSTWCGSPPY	-	0.2094	-	-	-	-	-	-	-
(Q9HBS3)	Homo sapiens	T336	KDRWRSMTVVPYLED	-	0.4507	-	-	-	-	-	-	-
STK11 (A0A0S2Z4D1)	Homo sapiens	T189	LLLTTGGTLKISDLG	-	0.2129	-	-	-	-	-	-	-
SNRK (A0A024R2Y6)	Homo sapiens	T173	QPGKKLTTSCGSLAY	-	0.2817	-	-	-	-	-	-	-
MARK1 (B4DIB3)	Homo sapiens	T215	TVGNKLDTFCGSPPY	-	0.2503	-	-	-	-	-	-	-

Help Instructions

Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)