CaMKinet | Result

Help Instruction

Double clicking on the substrate will redirect to the uniprot entry.
Clicking in the block having the substrate will zoom into its phophosites
Clicking the center of the circle will lead to zooming out.
Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
Clicking in the top right corner on the camara icon will download the image.

Sequence Logo

Graphics credits: Skylign

Substrate	Organism	PSite	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
CDKN1A * (P38936 )	Homo sapiens	S146	GRKRRQTSMTDFYHS	0.575	0.7163	TP	likely	experimental	73 \| 8 \|	20307683	-	In vitro
Eif4b (Q5RKG9)	Rattus norvegicus	S406	RPRERHPSWRSEETQ	-	0.8565	TP	certain	experimental	73 \| 8 \|	17234686	-	In vitro
Bad * (Q61337 )	Mus musculus	S136	PFRGRSRSAPPNLWA	-	0.6661	U	unlikely	experimental	214 \|	16403219	-	In vivo
Bad * (Q61337 )	Mus musculus	S155	GRELRRMSDEFEGSF	-	0.5456	U	unlikely	experimental	214 \|	16403219	-	In vivo
Bad (Q61337)	Mus musculus	S112	ETRSRHSSYPAGTEE	-	0.8828	TP	certain	experimental	72 \| 135 \| 133 \| 30 \| 73 \| 9 \|	16403219	-	-
CHEK1 (O14757)	Homo sapiens	S280	AKRPRVTSGGVSESP	0.246	0.6227	TP	certain	experimental	148 \| 72 \| 73 \| 55 \| 9 \|	23748345	-	-
TSC2 (P49815)	Homo sapiens	S1798	GQRKRLISSVEDFTE	0.406	0.247	TP	certain	experimental	72 \| 55 \| 9 \| 148 \|	23818547	-	-
Myc (P01108)	Mus musculus	S329	AKRAKLDSGRVLKQI	-	0.6375	TP	certain	experimental	72 \| 62 \| 73 \| 139 \|	18438430	-	-
EIF4B (P23588)	Homo sapiens	S406	RPRERHPSWRSEETQ	0.581	0.8462	TP	certain	experimental	40 \| 55 \| 9 \| 72 \| 9 \|	23749639	-	-
EIF4B (P23588)	Homo sapiens	S422	RERSRTGSESSQTGT	0.591	0.9457	TP	certain	experimental	40 \| 55 \| 9 \| 72 \| 9 \|	23749639	-	-
(Q9DUM3)	Human herpesvirus 8	S205	SLRKRRLSSPQGPST	-	0.9013	TP	certain	experimental	72 \| 73 \| 74 \| 20 \| 62 \|	19266083	-	-
(Q9DUM3)	Human herpesvirus 8	S206	LRKRRLSSPQGPSTL	-	0.8655	TP	certain	experimental	72 \| 73 \| 74 \| 20 \| 62 \|	19266083	-	-
CDKN1B (P46527)	Homo sapiens	T157	GIRKRPATDDSSTQN	0.142	0.8198	-	-	-	-	-	-	-
CDKN1A (P38936)	Homo sapiens	T145	QGRKRRQTSMTDFYH	0.981	0.725	TP	certain	experimental	72 \| 73 \| 9 \| 55 \|	20307683	-	-
PKM * (P14618 )	Homo sapiens	T454	RAPIIAVTRNPQTAR	0.805	0.433	TP	certain	experimental	66 \| 23 \| 3 \| 35 \| 55 \| 9 \| 72 \|	24142698	-	-
CDKN1B (P46527)	Homo sapiens	T198	PGLRRRQT_______	0.507	0.9488	-	-	-	-	-	-	-
Foxp3 (Q99JB6)	Mus musculus	S41	ELLGTRGSGGPFQGR	-	0.7951	TP	certain	not annotated	23 \| 3 \| 72 \| 73 \| 55 \| 214 \|	25987564	-	in-vitro and in-vivo
Notch1 (Q01705)	Mus musculus	S2152	GKKARKPSTKGLACG	-	0.712	TP	certain	experimental	73 \| 8 \| 148 \| 214 \| 55 \| 72 \|	27281612	-	in-vitro
IRS1 (P35568)	Homo sapiens	S1101	GCRRRHSSETFSSTP	0.923	0.8085	TP	certain	experimental	72 \| 140 \| 55 \|	26956053	-	in-vivo
Foxp3 (Q99JB6)	Mus musculus	S33	WKTAPKGSELLGTRG	-	0.7369	TP	certain	experimental	23 \| 3 \| 72 \| 73 \| 55 \| 214 \|	25987564	-	in-vitro and in-vivo
Myc * (P01108 )	Mus musculus	S329	AKRAKLDSGRVLKQI	-	0.6375	TP	certain	experimental	73 \| 72 \| 8 \| 55 \|	18438430	-	-
MYC (P01106)	Homo sapiens	S329	AKRVKLDSVRVLRQI	0.225	0.4979	TP	certain	predicted	-	18438430	-	-
MAP3K8 * (P41279 )	Homo sapiens	S400	EDQPRCQSLDSALLE	0.873	0.6482	TP	likely	experimental	73 \| 8 \|	15548703	-	-
MAP3K8 * (P41279 )	Homo sapiens	S413	LERKRLLSRKELELP	0.038	0.3631	TP	likely	experimental	73 \| 8 \|	15548703	-	-
MDM2 * (Q00987 )	Homo sapiens	S166	SSRRRAISETEENSD	0.815	0.7718	TP	likely	experimental	73 \|	19166854	-	-
MDM2 * (Q00987 )	Homo sapiens	S186	RQRKRHKSDSISLSF	0.958	0.6043	TP	likely	experimental	73 \|	19166854	-	-
EIF4EBP1 (Q13541)	Homo sapiens	S65	FLMECRNSPVTKTPP	0.902	0.708	TP	certain	experimental	72 \| 148 \| 55 \|	21937691	-	-
BAD (Q92934)	Homo sapiens	S118	GRELRRMSDEFVDSF	0.787	0.5758	-	-	-	-	-	-	-
BAD (Q92934)	Homo sapiens	S75	EIRSRHSSYPAGTED	0.509	0.8198	-	-	-	-	-	-	-
BAD (Q92934)	Homo sapiens	S99	PFRGRSRSAPPNLWA	0.900	0.7982	-	-	-	-	-	-	-
PIM2 (Q9P1W9)	Homo sapiens	S204	FDGTRVYSPPEWISR	0.580	0.2064	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S75	EIRSRHSSYPAGTED	-	0.853	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S99	PFRGRSRSAPPNLWA	-	0.8343	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S118	GRELRRMSDEFVDSF	-	0.6427	-	-	-	-	-	-	-
NOTCH1 (P46531)	Homo sapiens	S2162	GKKVRKPSSKGLACG	0.565	0.6269	-	-	-	-	-	-	-
(A8K7N7)	Homo sapiens	S33	WRAAPKASDLLGARG	-	0.7505	-	-	-	-	-	-	-
PIM2 (Q9P1W9)	Homo sapiens	T195	LLHDEPYTDFDGTRV	0.424	0.2988	-	-	-	-	-	-	-

Help Instructions

Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)