PID pathway - Regulation of nuclear SMAD2/3 signaling

 
 
Name Protein Names EntryName Phosphorylated by CaM kinases
AKT1 RAC-alpha serine/threonine-protein kinase; P31749 MAPKAPK2 | SIK2 | CAMKK2 | PRKD1 |
CDKN1A Cyclin-dependent kinase inhibitor 1; P38936 DAPK3 | PIM2 | PIM1 | Stk11 | DAPK1 | NUAK1 |
CEBPB CCAAT/enhancer-binding protein beta; P17676 CAMK2A | CAMK2B | CAMK2D | CAMK2G | RPS6KA1 |
CREB1 Cyclic AMP-responsive element-binding protein 1; P16220 RPS6KA4 | MAPKAPK2 | TSSK4 | CAMK1D | PRKD1 | CAMK4 | CAMK2A | CAMK2B | CAMK2D | CAMK2G | RPS6KA2 | RPS6KA3 | CAMK1 | CAMK1G | RPS6KA1 | RPS6KA5 |
CREBBP CREB-binding protein; Q92793 CAMK4 |
EP300 Histone acetyltransferase p300; Q09472 Camk4 | CAMK4 | CAMK1 | PRKAA1 | Prkaa2 | CAMK1D | CAMK1G |
ESR1 Estrogen receptor; P03372 RPS6KA3 | RPS6KA1 |
FOS Proto-oncogene c-Fos; P01100 RPS6KA2 | RPS6KA1 |
FOXO3 Forkhead box protein O3; O43524 PIM1 | PRKAA2 | PRKAA1 | MAPKAPK5 |
HNF4A Hepatocyte nuclear factor 4-alpha; P41235 Prkaa1 | PRKAA1 |
JUN Transcription factor AP-1; P05412 PRKD1 |
MEF2C Myocyte-specific enhancer factor 2C; Q06413 RPS6KA2 | MYLK2 |
RUNX3 Runt-related transcription factor 3; Q13761 PIM1 |
SMAD2 Mothers against decapentaplegic homolog 2; Q15796 Melk | CAMK2A | MELK |
SMAD4 Mothers against decapentaplegic homolog 4; Q13485 Melk | STK11 | MELK |