Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| TP53 (P04637) | Homo sapiens | S20 | PLSQETFSDLWKLLP | 0.567 | 0.6183 | TP | certain | experimental | 73 | 55 | 72 | 74 | 8 | | 17339337 | Non high throughput (17339337) |
|
| Dapk1 (Q80YE7) | Mus musculus | S308 | ARKKWKQSVRLISLC | - | 0.1048 | TP | certain | experimental | 427 | 74 | | 15729359 | Non high throughput (15729359) |
|
| MYL12B (O14950) | Homo sapiens | T19 | KKRPQRATSNVFAMF | 0.589 | 0.5296 | - | - | - | - | - | - | - |
| DAPK3 (O43293) | Homo sapiens | S309 | LKEYTIKSHSSLPPN | 0.436 | 0.5342 | TP | certain | - | 72 | 73 | 9 | | 15367680 | - | - |
| DAPK3 (O43293) | Homo sapiens | S312 | YTIKSHSSLPPNNSY | 0.916 | 0.4119 | TP | certain | - | 72 | 73 | 9 | | 15367680 | - | - |
| DAPK3 (O43293) | Homo sapiens | S318 | SSLPPNNSYADFERF | 0.015 | 0.4652 | TP | certain | - | 72 | 73 | 9 | | 15367680 | - | - |
| DAPK3 (O43293) | Homo sapiens | S326 | YADFERFSKVLEEAA | 0.671 | 0.3249 | TP | certain | - | 72 | 73 | 9 | | 15367680 | - | - |
| DDX58 (O95786) | Homo sapiens | S654 | IEGNPKLSFLKPGIL | 0.178 | 0.2164 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| DDX58 (O95786) | Homo sapiens | S764 | KEKMMNDSILRLQTW | 0.243 | 0.2783 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| DDX58 (O95786) | Homo sapiens | S8 | MTTEQRRSLQAFQDY | 0.048 | 0.2129 | TP | likely | - | 214 | 73 | | 28132841 | - | - |
| TPM1 (P09493) | Homo sapiens | S283 | HALNDMTSI______ | 0.284 | 0.5055 | TP | certain | - | 73 | 214 | 8 | 72 | | 17895359 | - | - |
| RPS6 (P62753) | Homo sapiens | S235 | IAKRRRLSSLRASTS | 0.272 | 0.6991 | TP | likely | - | 72 | 73 | 55 | 148 | | 18974095 | - | - |
| PIN1 (Q13526) | Homo sapiens | S71 | HSQSRRPSSWRQEKI | 0.725 | 0.5951 | TP | certain | - | 72 | 73 | 8 | 3 | 23 | 55 | 30 | 40 | | 21497122 | - | - |
| DAPK3 (O43293) | Homo sapiens | S311 | EYTIKSHSSLPPNNS | 0.624 | 0.5017 | TP | certain | - | 73 | 8 | | 15367680 | - | - |
| HSF1 (Q00613) | Homo sapiens | S230 | PKYSRQFSLEHVHGS | 0.584 | 0.5055 | TP | certain | - | 72 | 73 | 148 | 55 | | 25380824 | - | - |
| TP53 (P04637) | Homo sapiens | S269 | GNLLGRNSFEVRVCA | 0.232 | 0.3529 | TP | likely | - | 154 | | 20851891 | - | - |
| MDM2 (Q00987) | Homo sapiens | S166 | SSRRRAISETEENSD | 0.815 | 0.7718 | TP | certain | - | 161 | 131 | 9 | 73 | | 15001356 | - | - |
| MDM2 (Q00987) | Homo sapiens | S186 | RQRKRHKSDSISLSF | 0.958 | 0.6043 | TP | certain | - | 161 | 131 | 9 | 73 | | 15001356 | - | - |
| BECN1 (Q14457) | Homo sapiens | S90 | IPPARMMSTESANSF | 0.467 | 0.4582 | TP | likely | - | 148 | 55 | 73 | | 26994142 | - | - |
| DDX58 (O95786) | Homo sapiens | T667 | ILTGRGKTNQNTGMT | 0.181 | 0.5419 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| DDX58 (O95786) | Homo sapiens | T671 | RGKTNQNTGMTLPAQ | 0.243 | 0.4292 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| DDX58 (O95786) | Homo sapiens | T674 | TNQNTGMTLPAQKCI | 0.879 | 0.4051 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| DDX58 (O95786) | Homo sapiens | T770 | DSILRLQTWDEAVFR | 0.382 | 0.1528 | TP | likely | - | 73 | 74 | 55 | 214 | | 28132841 | - | - |
| BECN1 (Q14457) | Homo sapiens | T119 | LSRRLKVTGDLFDIM | 0.202 | 0.4017 | TP | certain | - | 73 | 3 | 9 | 214 | 55 | 8 | 74 | 30 | 40 | 107 | | 19180116 | - | - |
| DAPK3 (O43293) | Homo sapiens | T265 | KDPKRRMTIAQSLEH | 0.897 | 0.1914 | TP | certain | - | 72 | 73 | 273 | 135 | 8 | | 15611134 | - | - |
| DAPK3 (O43293) | Homo sapiens | T299 | PERRRLKTTRLKEYT | 0.621 | 0.4801 | TP | certain | - | 72 | 73 | 273 | 135 | 8 | 11 | 9 | | 15611134, 15367680 | - | - |
| DAPK3 (O43293) | Homo sapiens | T306 | TTRLKEYTIKSHSSL | 0.570 | 0.494 | TP | certain | - | 72 | 73 | 273 | 135 | 8 | | 15611134 | - | - |
| DAPK1 (P53355-1) | Homo sapiens | S313 | KQSVRLISLCQRLSR | - | 0.0888 | TP | certain | - | 73 | 8 | | 11579085 | - | - |
| DAPK1 (P53355-1) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | TP | certain | - | 72 | 73 | 55 | 8 | | 11579085 | - | - |
| CAMKK2 (Q96RR4) | Homo sapiens | S511 | RREERSLSAPGNLLT | 0.556 | 0.7843 | TP | certain | - | 66 | 74 | 30 | 62 | 55 | | 15209507 | - | - |
| DAPK1 (P53355) | Homo sapiens | S308 | ARKKWKQSVRLISLC | - | 0.1007 | TP | certain | - | 9 | 72 | 73 | | 11579085 | - | - |
| Stx1a (P32851) | Rattus norvegicus | S188 | IIMDSSISKQALSEI | - | 0.3356 | TP | certain | - | 62 | 66 | 72 | 73 | | 12730201 | - | - |
| MCM3 (P25205) | Homo sapiens | S160 | KTIERRYSDLTTLVA | 0.013 | 0.2609 | TP | certain | - | 62 | 55 | 45 | 72 | 73 | 9 | | 18283219 | - | - |
| TPM1 (P09493) | Homo sapiens | T282 | DHALNDMTSI_____ | 0.100 | 0.5577 | TP | certain | - | 45 | 9 | | 17895359 | - | - |
| Myl12b (Q3THE2) | Mus musculus | T19 | KKRPQRATSNVFAMF | - | 0.5296 | TP | certain | experimental | 72 | 73 | 3 | 9 | 273 | 55 | | 14600263 | Non high throughput (14600263) | - |
| MYL12B (O14950) | Homo sapiens | S20 | KRPQRATSNVFAMFD | 0.891 | 0.5577 | - | - | - | - | - | - |
|
| TP53 * (P04637 ) | Homo sapiens | T18 | EPPLSQETFSDLWKL | 0.691 | 0.6183 | - | - | - | - | - | - |
|
| RPL13A * (P40429 ) | Homo sapiens | S77 | PYHFRAPSRIFWRTV | 0.605 | 0.2094 | - | - | - | - | - | - |
|
| GRIN2B (Q13224) | Homo sapiens | S1303 | NKLRRQHSYDTFVDL | 0.872 | 0.5758 | TP | certain | experimental | 73 | 55 | 9 | | 20141836 | - |
|
| MYL12A * (P19105 ) | Homo sapiens | S19 | KRPQRATSNVFAMFD | 0.788 | 0.5577 | TP | certain | experimental | 73 | 8 | 72 | 55 | | 11485996 | - | - |
| MYL9 (P24844) | Homo sapiens | S20 | KRPQRATSNVFAMFD | 0.877 | 0.5577 | - | - | - | - | - | - | - |
| CDKN1A * (P38936 ) | Homo sapiens | S146 | GRKRRQTSMTDFYHS | 0.575 | 0.7163 | - | - | - | - | - | - | - |
| DAPK1 * (P53355 ) | Homo sapiens | S313 | KQSVRLISLCQRLSR | - | 0.0888 | TP | likely | - | 73 | 8 | | 11579085 | - | - |
| STX1A * (Q16623 ) | Homo sapiens | S188 | IIMDSSISKQALSEI | 0.028 | 0.3356 | - | - | - | - | - | - | - |
| (Q59H88) | Homo sapiens | S311 | ARKKWKQSVRLISLC | - | 0.1007 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)