Help Instruction
- Double clicking on the substrate will redirect to the uniprot entry.
- Clicking in the block having the substrate will zoom into its phophosites
- Clicking the center of the circle will lead to zooming out.
- Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
- The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
- Clicking in the top right corner on the camara icon will download the image.
| Substrate | Organism | PSite | Sequence(+/-7) | Conservation | Disorder | Curator Assessment | Reliability | Evidence Class | Evidence Logic | PubMed | Phospho-ELM | PhosphoSite-Plus |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| EP300 (Q09472) | Homo sapiens | S89 | SELLRSGSSPNLNMG | 0.391 | 0.6851 | - | - | - | - | - | - | - |
| Creb1 (P15337) | Rattus norvegicus | S133 | EILSRRPSYRKILND | - | 0.4979 | - | certain | experimental | 72 | 73 | 107 | 9 | | 7958915 | - |
|
| Myh9 (Q62812) | Rattus norvegicus | T1940 | RRIVRKGTGDCSDEE | - | 0.5176 | TP | certain | experimental | 72 | 55 | | 10945986 | - |
|
| HDAC5 (Q9UQL6) | Homo sapiens | S259 | FPLRKTASEPNLKVR | 0.835 | 0.6712 | TP | certain | experimental | 9 | 143 | | 11081517 | - | - |
| HDAC5 (Q9UQL6) | Homo sapiens | S498 | RPLSRTQSSPLPQSP | 0.940 | 0.9126 | TP | certain | experimental | 9 | 143 | | 11081517 | - | - |
| Crebbp (Q6JHU9) | Rattus norvegicus | S301 | PQLASKQSMVNSLPA | - | 0.5807 | TP | certain | experimental | 107 | 73 | 9 | 72 | 53 | 148 | | 11970865 | - | - |
| CAMK4 (Q16566) | Homo sapiens | S12 | TVPSCSASSCSSVTA | 0.500 | 0.1914 | TP | certain | experimental | 73 | 8 | 436 | | 8702940 | - | - |
| CAMK4 (Q16566) | Homo sapiens | S13 | VPSCSASSCSSVTAS | 0.500 | 0.2918 | TP | certain | experimental | 73 | 8 | 436 | | 8702940 | - | - |
| HNRNPL (P14866) | Homo sapiens | S544 | GKSERSSSGLLEWES | 0.656 | 0.3807 | TP | certain | experimental | 8 | 107 | 73 | 55 | 72 | 9 | | 22570490 | - | - |
| STMN1 (P16949) | Homo sapiens | S16 | KELEKRASGQAFELI | 0.337 | 0.4087 | TP | certain | experimental | 8 | 73 | 436 | 72 | 55 | 107 | 205 | | 9,15,48,45,79,25,472 | - | - |
| SIK2 (Q9H0K1) | Homo sapiens | T484 | RSGQRRHTLSEVTNQ | 0.896 | 0.6482 | TP | certain | experimental | 55 | 73 | 9 | | 21220102 | - | - |
| PHB2 (Q99623) | Homo sapiens | S91 | RARPRKISSPTGSKD | 0.185 | 0.4051 | TP | certain | experimental | 66 | 72 | 9 | | 21689744 | - | - |
| CABIN1 (Q9Y6J0) | Homo sapiens | S2126 | PEPSRAKSRPLPNMP | 0.526 | 0.9057 | TP | certain | experimental | 73 | 148 | 72 | 9 | | 15902271 | - | - |
| SRF (P11831) | Homo sapiens | S103 | RGLKRSLSEMEIGMV | 0.283 | 0.494 | TP | certain | experimental | 72 | 73 | 55 | | 7929249 | - | - |
| CREB1 (P16220) | Homo sapiens | S133 | EILSRRPSYRKILND | - | 0.4979 | TP | certain | experimental | 72 | 73 | 107 | 8 | | 7958915 | - | - |
| CAMK2A (Q9UQM7-2) | Homo sapiens | S332 | DGVKKRKSSSSVQLM | 0.087 | 0.5854 | TP | certain | experimental | 8 | 72 | 73 | | 9677407 | - | - |
| Crebbp (P45481) | Mus musculus | S301 | PQLASKQSMVNSLPA | - | 0.5758 | TP | certain | experimental | 72 | 205 | 9 | 53 | 73 | 148 | | 11970865 | - | - |
| LIMK1 (P53667) | Homo sapiens | T508 | PDRKKRYTVVGNPYW | 0.866 | 0.268 | U | likely | experimental | 72 | 55 | | 19696021 | - | - |
| Camk4 (P13234) | Rattus norvegicus | S437 | DQEMKRNSEETLKSV | - | 0.9488 | - | - | - | - | - | Non high throughput (8340352) | - |
| HDAC4 (P56524) | Homo sapiens | S467 | RPLGRTQSAPLPQNA | 0.904 | 0.8596 | - | - | - | - | - | Non high throughput (11470791) | - |
| HDAC4 (P56524) | Homo sapiens | S632 | RPLSRAQSSPASATF | 0.945 | 0.7289 | - | - | - | - | - | Non high throughput (11470791) | - |
| CREBBP (Q92793) | Homo sapiens | S302 | PQLASKQSMVNSLPT | 0.053 | 0.6136 | - | - | - | - | - | Non high throughput (11970865) | - |
| EP300 (Q09472) | Homo sapiens | S24 | KLSSPALSASASDGT | 0.267 | 0.6991 | - | - | - | - | - | Non high throughput (12590608) | - |
| Hspb1 (P14602) | Mus musculus | S15 | FSLLRSPSWEPFRDW | - | 0.1092 | - | - | - | - | - | - | - |
| Hspb1 (P14602) | Mus musculus | S86 | RALNRQLSSGVSEIR | - | 0.3599 | - | - | - | - | - | - | - |
| MYL12A (P19105) | Homo sapiens | S19 | KRPQRATSNVFAMFD | 0.788 | 0.5577 | - | - | - | - | - | - | - |
| RELA (Q04206) | Homo sapiens | S536 | SGDEDFSSIADMDFS | 0.319 | 0.2783 | - | - | - | - | - | - |
|
| Snf1lk2 (Q3LRT3) | Rattus norvegicus | T484 | RSGQRRHTLSEVTNQ | - | 0.6531 | - | - | - | - | - | - |
|
| NUMB (P49757-9) | Homo sapiens | S22 | EQLARQGSFRGFPAL | 0.728 | 0.5139 | - | - | - | - | - | - | - |
| HDAC4 (P56524) | Homo sapiens | S246 | FPLRKTASEPNLKLR | 0.871 | 0.6183 | - | - | - | - | - | - | - |
| HSPB1 (P04792) | Homo sapiens | S15 | FSLLRGPSWDPFRDW | 0.564 | 0.1323 | - | - | - | - | - | - | - |
| HSPB1 (P04792) | Homo sapiens | S82 | RALSRQLSSGVSEIR | 0.622 | 0.374 | - | - | - | - | - | - | - |
| NOS1 (B3VK56) | Homo sapiens | S852 | SYKVRFNSVSSYSDS | - | 0.346 | - | - | - | - | - | - | - |
| ACACA (Q13085) | Homo sapiens | S25 | RFIIGSVSEDNSEDE | 0.000 | 0.4901 | - | - | - | - | - | - | - |
| SYN1 (P17600) | Homo sapiens | S9 | NYLRRRLSDSNFMAN | 0.991 | 0.5533 | - | - | - | - | - | - | - |
| SNF1LK2 (A0A024R3G7) | Homo sapiens | T484 | RSGQRRHTLSEVTNQ | - | 0.6482 | - | - | - | - | - | - | - |
| CAMK1 (Q14012) | Homo sapiens | T177 | DPGSVLSTACGTPGY | 0.726 | 0.3215 | - | - | - | - | - | - | - |
Help Instructions
- Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
- The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
- The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
- The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
- In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
- Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)