AKT1 | RAC-alpha serine/threonine-protein kinase
 
 
Pathway ID Pathway Name (clicking on the name will redirect to Reactome)
R-HSA-109581 Apoptosis
R-HSA-109582 Hemostasis
R-HSA-109606 Intrinsic Pathway for Apoptosis
R-HSA-111447 Activation of BAD and translocation to mitochondria
R-HSA-114452 Activation of BH3-only proteins
R-HSA-1227986 Signaling by ERBB2
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1257604 PIP3 activates AKT signaling
R-HSA-1266738 Developmental Biology
R-HSA-1280215 Cytokine Signaling in Immune system
R-HSA-1280218 Adaptive Immune System
R-HSA-1358803 Downregulation of ERBB2:ERBB3 signaling
R-HSA-1430728 Metabolism
R-HSA-1445148 Translocation of SLC2A4 (GLUT4) to the plasma membrane
R-HSA-1474151 Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
R-HSA-157118 Signaling by NOTCH
R-HSA-162582 Signal Transduction
R-HSA-162582 Signal Transduction
R-HSA-1640170 Cell Cycle
R-HSA-1643685 Disease
R-HSA-165159 mTOR signalling
R-HSA-168256 Immune System
R-HSA-186712 Regulation of beta-cell development
R-HSA-194138 Signaling by VEGF
R-HSA-195721 Signaling by WNT
R-HSA-196854 Metabolism of vitamins and cofactors
R-HSA-198323 AKT phosphorylates targets in the cytosol
R-HSA-198323 AKT phosphorylates targets in the cytosol
R-HSA-198693 AKT phosphorylates targets in the nucleus
R-HSA-199418 Negative regulation of the PI3K/AKT network
R-HSA-199991 Membrane Trafficking
R-HSA-199991 Membrane Trafficking
R-HSA-201681 TCF dependent signaling in response to WNT
R-HSA-202131 Metabolism of nitric oxide: eNOS activation and regulation
R-HSA-203615 eNOS activation
R-HSA-210745 Regulation of gene expression in beta cells
R-HSA-211163 AKT-mediated inactivation of FOXO1A
R-HSA-212436 Generic Transcription Pathway
R-HSA-212436 Generic Transcription Pathway
R-HSA-2219528 PI3K/AKT Signaling in Cancer
R-HSA-354192 Integrin alphaIIb beta3 signaling
R-HSA-3700989 Transcriptional Regulation by TP53
R-HSA-372790 Signaling by GPCR
R-HSA-3769402 Deactivation of the beta-catenin transactivating complex
R-HSA-388396 GPCR downstream signalling
R-HSA-388841 Costimulation by the CD28 family
R-HSA-389356 CD28 co-stimulation
R-HSA-389357 CD28 dependent PI3K/Akt signaling
R-HSA-389513 CTLA4 inhibitory signaling
R-HSA-392451 G beta:gamma signalling through PI3Kgamma
R-HSA-397795 G-protein beta:gamma signalling
R-HSA-4420097 VEGFA-VEGFR2 Pathway
R-HSA-449147 Signaling by Interleukins
R-HSA-450385 Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA
R-HSA-450531 Regulation of mRNA stability by proteins that bind AU-rich elements
R-HSA-450604 KSRP (KHSRP) binds and destabilizes mRNA
R-HSA-453279 Mitotic G1-G1/S phases
R-HSA-5218920 VEGFR2 mediated vascular permeability
R-HSA-5357801 Programmed Cell Death
R-HSA-5628897 TP53 Regulates Metabolic Genes
R-HSA-5633007 Regulation of TP53 Activity
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5653656 Vesicle-mediated transport
R-HSA-5663202 Diseases of signal transduction
R-HSA-5674400 Constitutive Signaling by AKT1 E17K in Cancer
R-HSA-6785807 Interleukin-4 and Interleukin-13 signaling
R-HSA-6804757 Regulation of TP53 Degradation
R-HSA-6804758 Regulation of TP53 Activity through Acetylation
R-HSA-6804759 Regulation of TP53 Activity through Association with Co-factors
R-HSA-6806003 Regulation of TP53 Expression and Degradation
R-HSA-6807070 PTEN Regulation
R-HSA-6811558 PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
R-HSA-69202 Cyclin E associated events during G1/S transition
R-HSA-69206 G1/S Transition
R-HSA-69242 S Phase
R-HSA-69278 Cell Cycle, Mitotic
R-HSA-69656 Cyclin A:Cdk2-associated events at S phase entry
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-73857 RNA Polymerase II Transcription
R-HSA-74160 Gene expression (Transcription)
R-HSA-74160 Gene expression (Transcription)
R-HSA-76002 Platelet activation, signaling and aggregation
R-HSA-76009 Platelet Aggregation (Plug Formation)
R-HSA-8848021 Signaling by PTK6
R-HSA-8849469 PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1
R-HSA-8863795 Downregulation of ERBB2 signaling
R-HSA-8876198 RAB GEFs exchange GTP for GDP on RABs
R-HSA-8878166 Transcriptional regulation by RUNX2
R-HSA-8939211 ESR-mediated signaling
R-HSA-8941332 RUNX2 regulates genes involved in cell migration
R-HSA-8948751 Regulation of PTEN stability and activity
R-HSA-8953854 Metabolism of RNA
R-HSA-8978934 Metabolism of cofactors
R-HSA-9006921 Integrin signaling
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006925 Intracellular signaling by second messengers
R-HSA-9006927 Signaling by Non-Receptor Tyrosine Kinases
R-HSA-9006931 Signaling by Nuclear Receptors
R-HSA-9006934 Signaling by Receptor Tyrosine Kinases
R-HSA-9007101 Rab regulation of trafficking
R-HSA-9009391 Extra-nuclear estrogen signaling
R-HSA-9013694 Signaling by NOTCH4
R-HSA-9604323 Negative regulation of NOTCH4 signaling
R-HSA-9614085 FOXO-mediated transcription
R-HSA-9614399 Regulation of localization of FOXO transcription factors
R-HSA-9634638 Estrogen-dependent nuclear events downstream of ESR-membrane signaling
 
Pathway ID (clicking on the ID will display all the CaMKs and their Substrates) Pathway Name (clicking on the name will redirect to KEGG and will highlight all the CaMKs and Substrates in the pathway)
hsa04010 MAPK signaling pathway
hsa04012 ErbB signaling pathway
hsa04062 Chemokine signaling pathway
hsa04150 mTOR signaling pathway
hsa04210 Apoptosis
hsa04370 VEGF signaling pathway
hsa04380 Osteoclast differentiation
hsa04510 Focal adhesion
hsa04530 Tight junction
hsa04620 Toll-like receptor signaling pathway
hsa04630 Jak-STAT signaling pathway
hsa04660 T cell receptor signaling pathway
hsa04662 B cell receptor signaling pathway
hsa04664 Fc epsilon RI signaling pathway
hsa04666 Fc gamma R-mediated phagocytosis
hsa04722 Neurotrophin signaling pathway
hsa04725 Cholinergic synapse
hsa04910 Insulin signaling pathway
hsa04914 Progesterone-mediated oocyte maturation
hsa04920 Adipocytokine signaling pathway
hsa04973 Carbohydrate digestion and absorption
hsa05142 Chagas disease (American trypanosomiasis)
hsa05145 Toxoplasmosis
hsa05152 Tuberculosis
hsa05160 Hepatitis C
hsa05162 Measles
hsa05164 Influenza A
hsa05200 Pathways in cancer
hsa05210 Colorectal cancer
hsa05211 Renal cell carcinoma
hsa05212 Pancreatic cancer
hsa05213 Endometrial cancer
hsa05214 Glioma
hsa05215 Prostate cancer
hsa05218 Melanoma
hsa05220 Chronic myeloid leukemia
hsa05221 Acute myeloid leukemia
hsa05222 Small cell lung cancer
hsa05223 Non-small cell lung cancer
 
Pathway ID (clicking on the ID will display all the CaMKs and their Substrates) Pathway Name
a6b1_a6b4_integrin_pathway a6b1 and a6b4 Integrin signaling
amb2_neutrophils_pathway amb2 Integrin signaling
angiopoietinreceptor_pathway Angiopoietin receptor Tie2-mediated signaling
ar_pathway Coregulation of Androgen receptor activity
aurora_a_pathway Aurora A signaling
avb3_integrin_pathway Integrins in angiogenesis
bcr_5pathway BCR signaling pathway
cd8tcrpathway TCR signaling in naive CD8+ T cells
ceramidepathway Ceramide signaling pathway
endothelinpathway Endothelins
er_nongenomic_pathway Plasma membrane estrogen receptor signaling
fcer1pathway Fc-epsilon receptor I signaling in mast cells
fgf_pathway FGF signaling pathway
foxopathway FoxO family signaling
hedgehog_2pathway Signaling events mediated by the Hedgehog family
hedgehog_glipathway Hedgehog signaling events mediated by Gli proteins
hif1_tfpathway HIF-1-alpha transcription factor network
hnf3bpathway FOXA2 and FOXA3 transcription factor networks
ifngpathway IFN-gamma pathway
igf1_pathway IGF1 pathway
il2_pi3kpathway IL2 signaling events mediated by PI3K
il4_2pathway IL4-mediated signaling events
il6_7pathway IL6-mediated signaling events
insulin_glucose_pathway Insulin-mediated glucose transport
insulin_pathway Insulin Pathway
kitpathway Signaling events mediated by Stem cell factor receptor (c-Kit)
lymphangiogenesis_pathway VEGFR3 signaling in lymphatic endothelium
lysophospholipid_pathway LPA receptor mediated events
met_pathway Signaling events activated by Hepatocyte Growth Factor Receptor (c-Met)
mtor_4pathway mTOR signaling pathway
p75ntrpathway p75(NTR)-mediated signaling
pdgfrbpathway PDGFR-beta signaling pathway
pi3kciaktpathway Class I PI3K signaling events mediated by Akt
pi3kplctrkpathway Trk receptor signaling mediated by PI3K and PLC-gamma
ptp1bpathway Signaling events mediated by PTP1B
reelinpathway Reelin signaling pathway
retinoic_acid_pathway Retinoic acid receptors-mediated signaling
s1p_s1p3_pathway S1P3 pathway
smad2_3nuclearpathway Regulation of nuclear SMAD2/3 signaling
tcrpathway TCR signaling in naive CD4+ T cells
telomerasepathway Regulation of Telomerase
txa2pathway Thromboxane A2 receptor signaling
vegfr1_2_pathway Signaling events mediated by VEGFR1 and VEGFR2
vegfr1_pathway VEGFR1 specific signals