KEGG pathway - Progesterone-mediated oocyte maturation

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	PPP1R3A \| ESR2 \| CEBPB \| BAD \| ETV1 \| NFKBIB \| IRS1 \| EEF2K \| MITF \| FOS \| ESR1 \| Nr4a1 \| ITGB4 \| CREB1 \| SLC9A1 \| FLNA \| EIF4B \| NFKBIA \| L1CAM \| TSC2 \| Tsc2 \| GSK3B \| DAPK1 \| RPS6 \| YBX1 \| CCT2 \| MDM2 \| MXD1 \| Mitf \| RPS6KA1 \| Bad \| Kcnd3 \| Rps6ka1 \| Dlc1 \| Eif4b \| RPTOR \| DEPTOR \| CIC \| RANBP3 \| Krt17 \| METTL1 \| NDRG2 \| CARHSP1 \| Nos1 \| Cebpb \| CDKN1B \| VASP \| GMFB \| Cebpb \| UBR5 \| Mapk7 \| MAPK7 \| WWC1 \| Gab2 \| CDC25C \| CHEK1 \| PDCD4 \| SOS1 \| LCP1 \| APAF1 \| Senp2 \| OSTF1 \| CDC25A \| EPHA2 \| CDC25B \| SLC9A3R1 \| CDC34 \| SENP2 \|
RPS6KA2	Ribosomal protein S6 kinase alpha-2;	Q15349	BAD \| CREB1 \| RRN3 \| CDKN1B \| ATF4 \| Atf4 \| NFATC4 \| DAPK1 \| MEF2C \| FOS \| RPS6KA2 \|
RPS6KA3	Ribosomal protein S6 kinase alpha-3;	P51812	Mybpc3 \| PFKFB2 \| CIC \| KCNK3 \| ESR1 \| EIF2S1 \| Nr4a1 \| Htr2a \| Creb1 \| ATF4 \| EIF2AK2 \| Cebpb \| NFKBIA \| HIST1H2BB \| STAT3 \| Gata4 \| CDKN1B \| GSK3A \| GSK3B \| DAPK1 \| RPS6 \| YBX1 \| PPP1R3A \| NFATC4 \| RRN3 \| CREB1 \| HMGN1 \| TH \| TH \| TH \| PFKFB2 \| Mybpc3 \| Rps6 \| HIST1H3A \| H3F3A \| PPP1R3A \| BAD \| RANBP3 \| MAP3K5 \| WWC1 \| TH \| TINF2 \| LCP1 \| TBX21 \| FGFR1 \| STMN1 \| EPHA2 \| SLC9A3 \| CASP8 \|
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	PPP1R3A \| ESR2 \| CEBPB \| BAD \| ETV1 \| NFKBIB \| IRS1 \| EEF2K \| MITF \| FOS \| ESR1 \| Nr4a1 \| ITGB4 \| CREB1 \| SLC9A1 \| FLNA \| EIF4B \| NFKBIA \| L1CAM \| TSC2 \| Tsc2 \| GSK3B \| DAPK1 \| RPS6 \| YBX1 \| CCT2 \| MDM2 \| MXD1 \| Mitf \| RPS6KA1 \| Bad \| Kcnd3 \| Rps6ka1 \| Dlc1 \| Eif4b \| RPTOR \| DEPTOR \| CIC \| RANBP3 \| Krt17 \| METTL1 \| NDRG2 \| CARHSP1 \| Nos1 \| Cebpb \| CDKN1B \| VASP \| GMFB \| Cebpb \| UBR5 \| Mapk7 \| MAPK7 \| WWC1 \| Gab2 \| CDC25C \| CHEK1 \| PDCD4 \| SOS1 \| LCP1 \| APAF1 \| Senp2 \| OSTF1 \| CDC25A \| EPHA2 \| CDC25B \| SLC9A3R1 \| CDC34 \| SENP2 \|

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	MAPKAPK2 \| RPS6KA1 \|
RPS6KA2	Ribosomal protein S6 kinase alpha-2;	Q15349	RPS6KA2 \|
RPS6KA3	Ribosomal protein S6 kinase alpha-3;	P51812	MAPKAPK2 \|
AKT1	RAC-alpha serine/threonine-protein kinase;	P31749	MAPKAPK2 \| SIK2 \| CAMKK2 \| PRKD1 \|
CDC25A	M-phase inducer phosphatase 1;	P30304	CHEK1 \| PIM1 \| CHEK2 \| RPS6KA1 \|
CDC25B	M-phase inducer phosphatase 2;	P30305	MELK \| MAPKAPK2 \| BRSK1 \| CHEK1 \| RPS6KA1 \|
CDC25C	M-phase inducer phosphatase 3;	P30307	Mark3 \| BRSK1 \| MARK3 \| MAPKAPK2 \| CHEK2 \| CHEK1 \| RPS6KA1 \|
HSP90AA1	Heat shock protein HSP 90-alpha;	P07900	PNCK \|
HSP90AB1	Heat shock protein HSP 90-beta;	P08238	PNCK \|
PLK1	Serine/threonine-protein kinase PLK1;	P53350	MAPKAPK2 \|
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	MAPKAPK2 \| RPS6KA1 \|
CDC25B	M-phase inducer phosphatase 2;	P30305	MELK \| MAPKAPK2 \| BRSK1 \| CHEK1 \| RPS6KA1 \|