PID pathway - VEGFR3 signaling in lymphatic endothelium

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	PPP1R3A \| ESR2 \| CEBPB \| BAD \| ETV1 \| NFKBIB \| IRS1 \| EEF2K \| MITF \| FOS \| ESR1 \| Nr4a1 \| ITGB4 \| CREB1 \| SLC9A1 \| FLNA \| EIF4B \| NFKBIA \| L1CAM \| TSC2 \| Tsc2 \| GSK3B \| DAPK1 \| RPS6 \| YBX1 \| CCT2 \| MDM2 \| MXD1 \| Mitf \| RPS6KA1 \| Bad \| Kcnd3 \| Rps6ka1 \| Dlc1 \| Eif4b \| RPTOR \| DEPTOR \| CIC \| RANBP3 \| Krt17 \| METTL1 \| NDRG2 \| CARHSP1 \| Nos1 \| Cebpb \| CDKN1B \| VASP \| GMFB \| Cebpb \| UBR5 \| Mapk7 \| MAPK7 \| WWC1 \| Gab2 \| CDC25C \| CHEK1 \| PDCD4 \| SOS1 \| LCP1 \| APAF1 \| Senp2 \| OSTF1 \| CDC25A \| EPHA2 \| CDC25B \| SLC9A3R1 \| CDC34 \| SENP2 \|
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	PPP1R3A \| ESR2 \| CEBPB \| BAD \| ETV1 \| NFKBIB \| IRS1 \| EEF2K \| MITF \| FOS \| ESR1 \| Nr4a1 \| ITGB4 \| CREB1 \| SLC9A1 \| FLNA \| EIF4B \| NFKBIA \| L1CAM \| TSC2 \| Tsc2 \| GSK3B \| DAPK1 \| RPS6 \| YBX1 \| CCT2 \| MDM2 \| MXD1 \| Mitf \| RPS6KA1 \| Bad \| Kcnd3 \| Rps6ka1 \| Dlc1 \| Eif4b \| RPTOR \| DEPTOR \| CIC \| RANBP3 \| Krt17 \| METTL1 \| NDRG2 \| CARHSP1 \| Nos1 \| Cebpb \| CDKN1B \| VASP \| GMFB \| Cebpb \| UBR5 \| Mapk7 \| MAPK7 \| WWC1 \| Gab2 \| CDC25C \| CHEK1 \| PDCD4 \| SOS1 \| LCP1 \| APAF1 \| Senp2 \| OSTF1 \| CDC25A \| EPHA2 \| CDC25B \| SLC9A3R1 \| CDC34 \| SENP2 \|

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	MAPKAPK2 \| RPS6KA1 \|
AKT1	RAC-alpha serine/threonine-protein kinase;	P31749	MAPKAPK2 \| SIK2 \| CAMKK2 \| PRKD1 \|
CREB1	Cyclic AMP-responsive element-binding protein 1;	P16220	RPS6KA4 \| MAPKAPK2 \| TSSK4 \| CAMK1D \| PRKD1 \| CAMK4 \| CAMK2A \| CAMK2B \| CAMK2D \| CAMK2G \| RPS6KA2 \| RPS6KA3 \| CAMK1 \| CAMK1G \| RPS6KA1 \| RPS6KA5 \|
ITGB1	Integrin beta-1;	P05556	CAMK2A \|
RPS6KA1	Ribosomal protein S6 kinase alpha-1;	Q15418	MAPKAPK2 \| RPS6KA1 \|
SHC1	SHC-transforming protein 1;	P29353	Mapkapk2 \| MAPKAPK2 \|