KEGG pathway - ErbB signaling pathway

Name Synonyms EntryName Phosphorylate Substrates
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 KCND2 | Nos1 | PLCB3 | Nlgn1 | TH | Pln | Gabrg2 | Gabrb1 | ERBB2 | ITPKA | EGFR | HSF1 | ALOX5 | ETS1 | PPP1R14A | RYR2 | Myog | CLCN3 | HRH1 | Il6st | CAMK2A | Nos1 | NOS1 | VIM | Ryr2 | Ryr2 | Trpv1 | Syn1 | NEFL | CALD1 | TH | CACNA1S | Gja1 | MPZ | MAPT | Camk2a | Mylk | SRF | ETS2 | Lipe | Creb1 | CACNA1C | CACNA1C | CD44 | Ptpra | Spr | Drd3 | Gria1 | Gria4 | FLNA | Gjc1 | TCAP | MAPT | Vim | Dlg4 | Oprm1 | Ptk2 | SPR | OPRM1 | SNCA | GRIA1 | CDKN1B | Rph3a | VIM | RRAD | PLN | Cdk5r1 | Mecp2 | Grin2b | Cacna1c | Cacna1b | GFPT1 | GRIN2B | ESPL1 | SMAD2 | Dlg1 | Kcnd2 | Tph2 | RCHY1 | CARD11 | Rims1 | Pdc | Lrp4 | Gabbr1 | PEA15 | FBXO43 | Brsk1 | SLN | ITGB1BP1 | ITGB1 | Chrm4 | TNNT2 | PLN | CHAT | GLO1 | Myh9 | Sln | Sln | | NCOR2 | Itpr2 | HDAC5 | Mcu | Mybpc3 | TH | Kif3a | Slc6a3 | STMN1 | Cpeb3 | KIF3A | Ppp3ca | DAGLA | Abi1 | NOX5 | SLC6A4 | Syngap1 | KCNQ2 | Neto2 | CTNNB1 | BECN1 | DLGAP1 | Wee2 | ID1 | Fosb | NR1H2 | Psmc5 | KCNJ11 | Grm1 | SLC1A3 | Trpc6 | Dpysl2 | TNNT2 | DLG1 | GABRG2 | PDC | CLCN3 | PTPRA | BCL10 | KRT18 | MAPT | MAPT | CREB1 | ATP2A2 | PTPRA | PDC | DRD3 | DLG1 | IRF3 | ABI1 | HOMER3 | RYR2 | TRPV1 | SYN1 | NEFL | CACNA1S | | MPZ | CAMK2A | CALD1 | CALD1 | | CACNA1C | CACNA1C | GRIA4 | | GJC1 | MAPT | NOS1 | DLG4 | PTK2 | RPH3A | GABRB1 | CDK5R1 | IL6ST | MECP2 | CACNA1B | KCND2 | TPH2 | RIMS1 | LRP4 | | PEA15 | | GFAP | | PDC | SYNGAP1 | MCU | MYBPC3 | KIF3A | SLC6A3 | CPEB3 | PPP3CA | FOSB | | ATP2A2 | CEBPB | CFL2 | ADCY3 | QDPR | GFAP | ACACA | RYR1 | PPP1R9B | MYLK | ITGB1BP1 | CHAT | BRSK1 | CHRM4 | MYF4 | SLN | nlgn1 | GRM1 | TRPC6 | | VPS72 | |
CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta; Q13554 Gsk3b | RYR1 | CAMK2B | STMN1 | Gsk3a | PRKAA1 | DLGAP1 | OCLN | GRIN2B | GSK3A | GSK3B | TH | CREB1 | ATP2A2 | CEBPB | FLNA | PEA15 | CFL2 | DLG1 | ADCY3 | KRT18 | QDPR | GFAP | GRIA1 | HSF1 | PLCB3 | KCND2 | SYN1 | ACACA | RYR1 | VIM | RYR2 | PPP3CA | OPRM1 | PPP1R9B | PLN | CAMK2B | VPS72 | | CAMK2A |
CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta; Q13557 Ryr2 | ANKRD28 | HDAC4 | SCN5A | CACNB2 | Itpr2 | Pln | CEACAM1 | TTN | OCLN | KCNJ11 | VIM | CREB1 | TPD52 | HSF1 | ITPR2 | HIST3H3 | SSH1 | RYR2 | HDAC5 | RYR2 | PLN | TH | ATP2A2 | CEBPB | FLNA | PEA15 | CFL2 | DLG1 | ADCY3 | KRT18 | QDPR | GFAP | GRIA1 | PLCB3 | KCND2 | SYN1 | ACACA | RYR1 | PPP3CA | GRIN2B | OPRM1 | PPP1R9B | CAMK2D | VPS72 | | CAMK2A |
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma; Q13555 Bad | STAT3 | RELA | RARA | CAMK2G | DAB2 | OCLN | RRAD | BAD | | | TH | | RYR1 | STAT1 | GRIA1 | PEA15 | CREB1 | ATP2A2 | CEBPB | FLNA | CFL2 | DLG1 | ADCY3 | KRT18 | QDPR | GFAP | HSF1 | PLCB3 | KCND2 | SYN1 | ACACA | VIM | RYR2 | PPP3CA | GRIN2B | OPRM1 | PPP1R9B | VPS72 | PLN | | CAMK2A |
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 KCND2 | Nos1 | PLCB3 | Nlgn1 | TH | Pln | Gabrg2 | Gabrb1 | ERBB2 | ITPKA | EGFR | HSF1 | ALOX5 | ETS1 | PPP1R14A | RYR2 | Myog | CLCN3 | HRH1 | Il6st | CAMK2A | Nos1 | NOS1 | VIM | Ryr2 | Ryr2 | Trpv1 | Syn1 | NEFL | CALD1 | TH | CACNA1S | Gja1 | MPZ | MAPT | Camk2a | Mylk | SRF | ETS2 | Lipe | Creb1 | CACNA1C | CACNA1C | CD44 | Ptpra | Spr | Drd3 | Gria1 | Gria4 | FLNA | Gjc1 | TCAP | MAPT | Vim | Dlg4 | Oprm1 | Ptk2 | SPR | OPRM1 | SNCA | GRIA1 | CDKN1B | Rph3a | VIM | RRAD | PLN | Cdk5r1 | Mecp2 | Grin2b | Cacna1c | Cacna1b | GFPT1 | GRIN2B | ESPL1 | SMAD2 | Dlg1 | Kcnd2 | Tph2 | RCHY1 | CARD11 | Rims1 | Pdc | Lrp4 | Gabbr1 | PEA15 | FBXO43 | Brsk1 | SLN | ITGB1BP1 | ITGB1 | Chrm4 | TNNT2 | PLN | CHAT | GLO1 | Myh9 | Sln | Sln | | NCOR2 | Itpr2 | HDAC5 | Mcu | Mybpc3 | TH | Kif3a | Slc6a3 | STMN1 | Cpeb3 | KIF3A | Ppp3ca | DAGLA | Abi1 | NOX5 | SLC6A4 | Syngap1 | KCNQ2 | Neto2 | CTNNB1 | BECN1 | DLGAP1 | Wee2 | ID1 | Fosb | NR1H2 | Psmc5 | KCNJ11 | Grm1 | SLC1A3 | Trpc6 | Dpysl2 | TNNT2 | DLG1 | GABRG2 | PDC | CLCN3 | PTPRA | BCL10 | KRT18 | MAPT | MAPT | CREB1 | ATP2A2 | PTPRA | PDC | DRD3 | DLG1 | IRF3 | ABI1 | HOMER3 | RYR2 | TRPV1 | SYN1 | NEFL | CACNA1S | | MPZ | CAMK2A | CALD1 | CALD1 | | CACNA1C | CACNA1C | GRIA4 | | GJC1 | MAPT | NOS1 | DLG4 | PTK2 | RPH3A | GABRB1 | CDK5R1 | IL6ST | MECP2 | CACNA1B | KCND2 | TPH2 | RIMS1 | LRP4 | | PEA15 | | GFAP | | PDC | SYNGAP1 | MCU | MYBPC3 | KIF3A | SLC6A3 | CPEB3 | PPP3CA | FOSB | | ATP2A2 | CEBPB | CFL2 | ADCY3 | QDPR | GFAP | ACACA | RYR1 | PPP1R9B | MYLK | ITGB1BP1 | CHAT | BRSK1 | CHRM4 | MYF4 | SLN | nlgn1 | GRM1 | TRPC6 | | VPS72 | |
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 KCND2 | Nos1 | PLCB3 | Nlgn1 | TH | Pln | Gabrg2 | Gabrb1 | ERBB2 | ITPKA | EGFR | HSF1 | ALOX5 | ETS1 | PPP1R14A | RYR2 | Myog | CLCN3 | HRH1 | Il6st | CAMK2A | Nos1 | NOS1 | VIM | Ryr2 | Ryr2 | Trpv1 | Syn1 | NEFL | CALD1 | TH | CACNA1S | Gja1 | MPZ | MAPT | Camk2a | Mylk | SRF | ETS2 | Lipe | Creb1 | CACNA1C | CACNA1C | CD44 | Ptpra | Spr | Drd3 | Gria1 | Gria4 | FLNA | Gjc1 | TCAP | MAPT | Vim | Dlg4 | Oprm1 | Ptk2 | SPR | OPRM1 | SNCA | GRIA1 | CDKN1B | Rph3a | VIM | RRAD | PLN | Cdk5r1 | Mecp2 | Grin2b | Cacna1c | Cacna1b | GFPT1 | GRIN2B | ESPL1 | SMAD2 | Dlg1 | Kcnd2 | Tph2 | RCHY1 | CARD11 | Rims1 | Pdc | Lrp4 | Gabbr1 | PEA15 | FBXO43 | Brsk1 | SLN | ITGB1BP1 | ITGB1 | Chrm4 | TNNT2 | PLN | CHAT | GLO1 | Myh9 | Sln | Sln | | NCOR2 | Itpr2 | HDAC5 | Mcu | Mybpc3 | TH | Kif3a | Slc6a3 | STMN1 | Cpeb3 | KIF3A | Ppp3ca | DAGLA | Abi1 | NOX5 | SLC6A4 | Syngap1 | KCNQ2 | Neto2 | CTNNB1 | BECN1 | DLGAP1 | Wee2 | ID1 | Fosb | NR1H2 | Psmc5 | KCNJ11 | Grm1 | SLC1A3 | Trpc6 | Dpysl2 | TNNT2 | DLG1 | GABRG2 | PDC | CLCN3 | PTPRA | BCL10 | KRT18 | MAPT | MAPT | CREB1 | ATP2A2 | PTPRA | PDC | DRD3 | DLG1 | IRF3 | ABI1 | HOMER3 | RYR2 | TRPV1 | SYN1 | NEFL | CACNA1S | | MPZ | CAMK2A | CALD1 | CALD1 | | CACNA1C | CACNA1C | GRIA4 | | GJC1 | MAPT | NOS1 | DLG4 | PTK2 | RPH3A | GABRB1 | CDK5R1 | IL6ST | MECP2 | CACNA1B | KCND2 | TPH2 | RIMS1 | LRP4 | | PEA15 | | GFAP | | PDC | SYNGAP1 | MCU | MYBPC3 | KIF3A | SLC6A3 | CPEB3 | PPP3CA | FOSB | | ATP2A2 | CEBPB | CFL2 | ADCY3 | QDPR | GFAP | ACACA | RYR1 | PPP1R9B | MYLK | ITGB1BP1 | CHAT | BRSK1 | CHRM4 | MYF4 | SLN | nlgn1 | GRM1 | TRPC6 | | VPS72 | |
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma; Q13555 Bad | STAT3 | RELA | RARA | CAMK2G | DAB2 | OCLN | RRAD | BAD | | | TH | | RYR1 | STAT1 | GRIA1 | PEA15 | CREB1 | ATP2A2 | CEBPB | FLNA | CFL2 | DLG1 | ADCY3 | KRT18 | QDPR | GFAP | HSF1 | PLCB3 | KCND2 | SYN1 | ACACA | VIM | RYR2 | PPP3CA | GRIN2B | OPRM1 | PPP1R9B | VPS72 | PLN | | CAMK2A |
 
Name Protein Names EntryName Phosphorylated by CaM kinases
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 CAMK2A |
CAMK2B Calcium/calmodulin-dependent protein kinase type II subunit beta; Q13554 CAMK2B |
CAMK2D Calcium/calmodulin-dependent protein kinase type II subunit delta; Q13557 CAMK2D |
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma; Q13555 CAMK2G |
AKT1 RAC-alpha serine/threonine-protein kinase; P31749 MAPKAPK2 | SIK2 | CAMKK2 | PRKD1 |
BAD Bcl2-associated agonist of cell death; Q92934 PIM1 | PIM2 | PIM3 | CAMK2G | RPS6KA2 | RPS6KA1 | CHEK1 | PRKD1 | RPS6KA3 |
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 CAMK2A |
CAMK2A Calcium/calmodulin-dependent protein kinase type II subunit alpha; Q9UQM7 CAMK2A |
CAMK2G Calcium/calmodulin-dependent protein kinase type II subunit gamma; Q13555 CAMK2G |
CDKN1A Cyclin-dependent kinase inhibitor 1; P38936 DAPK3 | PIM2 | PIM1 | Stk11 | DAPK1 | NUAK1 |
CDKN1B Cyclin-dependent kinase inhibitor 1B; P46527 RPS6KA3 | PRKAA1 | CAMK1 | PIM1 | PIM2 | PIM3 | CAMK2A | RPS6KA2 | RPS6KA1 |
EGFR Epidermal growth factor receptor; P00533 PRKD1 | CAMK2A | PRKAA1 |
ELK1 ETS domain-containing protein Elk-1; P19419 RPS6KA5 |
ERBB2 Receptor tyrosine-protein kinase erbB-2; P04626 CAMK2A | PRKAA1 |
GSK3B Glycogen synthase kinase-3 beta; P49841 RPS6KA3 | CAMK2B | PRKD3 | RPS6KA1 | STK11 |
JUN Transcription factor AP-1; P05412 PRKD1 |
PAK1 Serine/threonine-protein kinase PAK 1; Q13153 BRSK2 | STK11 |
SHC1 SHC-transforming protein 1; P29353 Mapkapk2 | MAPKAPK2 |