CaM Kinases known in this pathway:
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| DAPK1 | Death-associated protein kinase 1; | P53355 | RPS6KA3 | DAPK1 | DAPK2 | DAPK3 | RPS6KA2 | RPS6KA1 | STK17A | STK17B | |
| DAPK2 | Death-associated protein kinase 2; | Q9UIK4 | DAPK2 | |
| DAPK3 | Death-associated protein kinase 3; | O43293 | DAPK3 | DAPK1 | |
| TP53 | Cellular tumor antigen p53; | P04637 | DAPK3 | CHEK1 | STK11 | DAPK1 | MAPKAPK2 | NUAK1 | MAPKAPK5 | STK17A | CHEK2 | MELK | PRKAA1 | PRKAA2 | SIK1 | |
| VHL | von Hippel-Lindau disease tumor suppressor; | P40337 | CHEK2 | |
| AKT1 | RAC-alpha serine/threonine-protein kinase; | P31749 | MAPKAPK2 | SIK2 | CAMKK2 | PRKD1 | |
| BAD | Bcl2-associated agonist of cell death; | Q92934 | PIM1 | PIM2 | PIM3 | CAMK2G | RPS6KA2 | RPS6KA1 | CHEK1 | PRKD1 | RPS6KA3 | |
| BCL2L1 | Bcl-2-like protein 1; | Q07817 | MAPKAPK2 | |
| CDKN1A | Cyclin-dependent kinase inhibitor 1; | P38936 | DAPK3 | PIM2 | PIM1 | Stk11 | DAPK1 | NUAK1 | |
| CDKN1B | Cyclin-dependent kinase inhibitor 1B; | P46527 | RPS6KA3 | PRKAA1 | CAMK1 | PIM1 | PIM2 | PIM3 | CAMK2A | RPS6KA2 | RPS6KA1 | |
| CREBBP | CREB-binding protein; | Q92793 | CAMK4 | |
| CTNNB1 | Catenin beta-1; | P35222 | PRKD1 | CAMK2A | PRKAA2 | |
| DAPK1 | Death-associated protein kinase 1; | P53355 | RPS6KA3 | DAPK1 | DAPK2 | DAPK3 | RPS6KA2 | RPS6KA1 | STK17A | STK17B | |
| DAPK2 | Death-associated protein kinase 2; | Q9UIK4 | DAPK2 | |
| DAPK3 | Death-associated protein kinase 3; | O43293 | DAPK3 | DAPK1 | |
| E2F1 | Transcription factor E2F1; | Q01094 | MAPKAPK2 | CHEK2 | |
| E2F3 | Transcription factor E2F3; | O00716 | CHEK1 | CHEK2 | |
| EGFR | Epidermal growth factor receptor; | P00533 | PRKD1 | CAMK2A | PRKAA1 | |
| EP300 | Histone acetyltransferase p300; | Q09472 | Camk4 | CAMK4 | CAMK1 | PRKAA1 | Prkaa2 | CAMK1D | CAMK1G | |
| ERBB2 | Receptor tyrosine-protein kinase erbB-2; | P04626 | CAMK2A | PRKAA1 | |
| ETS1 | Protein C-ets-1; | P14921 | CAMK2A | |
| FOS | Proto-oncogene c-Fos; | P01100 | RPS6KA2 | RPS6KA1 | |
| GSK3B | Glycogen synthase kinase-3 beta; | P49841 | RPS6KA3 | CAMK2B | PRKD3 | RPS6KA1 | STK11 | |
| HSP90AA1 | Heat shock protein HSP 90-alpha; | P07900 | PNCK | |
| HSP90AB1 | Heat shock protein HSP 90-beta; | P08238 | PNCK | |
| IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta; | O14920 | PRKAA2 | |
| ITGB1 | Integrin beta-1; | P05556 | CAMK2A | |
| JUN | Transcription factor AP-1; | P05412 | PRKD1 | |
| MDM2 | E3 ubiquitin-protein ligase Mdm2; | Q00987 | MAPKAPK2 | PIM1 | DAPK1 | PIM2 | DAPK3 | RPS6KA1 | |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit; | P19838 | CHEK1 | |
| NFKBIA | NF-kappa-B inhibitor alpha; | P25963 | RPS6KA3 | RPS6KA1 | |
| PLD1 | Phospholipase D1; | Q13393 | PRKAA2 | |
| PML | Protein PML; | P29590 | CHEK2 | |
| PTEN | Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN; | P60484 | STK11 | |
| RB1 | Retinoblastoma-associated protein; | P06400 | CHEK1 | CHEK2 | |
| RELA | Transcription factor p65; | Q04206 | RPS6KA4 | PIM1 | CAMK2G | RPS6KA5 | CAMK4 | CHEK1 | |
| SKP2 | S-phase kinase-associated protein 2; | Q13309 | Pim1 | PIM1 | |
| SMAD2 | Mothers against decapentaplegic homolog 2; | Q15796 | Melk | CAMK2A | MELK | |
| SMAD4 | Mothers against decapentaplegic homolog 4; | Q13485 | Melk | STK11 | MELK | |
| STAT3 | Signal transducer and activator of transcription 3; | P40763 | RPS6KA3 | CAMK2G | Dapk3 | DAPK3 | |