PID pathway - IGF1 pathway

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
PRKD1	Serine/threonine-protein kinase D1;	Q15139	TFAP2A \| COL4A3BP \| CTTN \| CREB1 \| Dlc1 \| SNAI1 \| MARK2 \| VASP \| PAK4 \| Evl \| RIN1 \| PI4KB \| Kidins220 \| SSH1 \| HSPB1 \| EGFR \| CTNNB1 \| PRKD1 \| Prkd1 \| PPP1R14A \| HDAC7 \| TLR4 \| TLR5 \| MBP \| JUN \| CACNA1C \| OSBP \| CFL1 \| Tnni3 \| Pik3r1 \| AKT1 \| Syk \| Tnni3 \| CACNA1C \| MYBPC3 \| Ahcyl1 \| MAP4K1 \| BAD \| DLC1 \| SPHK2 \| PI4KB \| HDAC5 \| PTRH2 \| PIP4K2A \| TCAP \| Prkaa1 \| DNM1L \| Prkaa2 \| Cdh2 \| RABEP1 \| REM1 \| Plekhg5 \| OSBP \| Drd1 \| Mybpc3 \| RTKN \| ARFIP1 \| ARFIP1 \| Nlrp3 \| HSPB6 \| MAP3K5 \| ITGB4 \| PLEKHG5 \| CACNA1C \| AHCYL1 \| TNNI3 \| PIK3R1 \| SYK \| TRPV1 \| HDAC7 \| RTKN \| HDAC5 \| SYK \| PRKD1 \| AHCYL1 \| KIDINS220 \| EVL \| PLCG1 variant protein \| PRKAA1 \| \| DRD1 \| MYBPC3 \|
PRKD1	Serine/threonine-protein kinase D1;	Q15139	TFAP2A \| COL4A3BP \| CTTN \| CREB1 \| Dlc1 \| SNAI1 \| MARK2 \| VASP \| PAK4 \| Evl \| RIN1 \| PI4KB \| Kidins220 \| SSH1 \| HSPB1 \| EGFR \| CTNNB1 \| PRKD1 \| Prkd1 \| PPP1R14A \| HDAC7 \| TLR4 \| TLR5 \| MBP \| JUN \| CACNA1C \| OSBP \| CFL1 \| Tnni3 \| Pik3r1 \| AKT1 \| Syk \| Tnni3 \| CACNA1C \| MYBPC3 \| Ahcyl1 \| MAP4K1 \| BAD \| DLC1 \| SPHK2 \| PI4KB \| HDAC5 \| PTRH2 \| PIP4K2A \| TCAP \| Prkaa1 \| DNM1L \| Prkaa2 \| Cdh2 \| RABEP1 \| REM1 \| Plekhg5 \| OSBP \| Drd1 \| Mybpc3 \| RTKN \| ARFIP1 \| ARFIP1 \| Nlrp3 \| HSPB6 \| MAP3K5 \| ITGB4 \| PLEKHG5 \| CACNA1C \| AHCYL1 \| TNNI3 \| PIK3R1 \| SYK \| TRPV1 \| HDAC7 \| RTKN \| HDAC5 \| SYK \| PRKD1 \| AHCYL1 \| KIDINS220 \| EVL \| PLCG1 variant protein \| PRKAA1 \| \| DRD1 \| MYBPC3 \|

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
PRKD1	Serine/threonine-protein kinase D1;	Q15139	PRKD3 \| PRKD1 \|
AKT1	RAC-alpha serine/threonine-protein kinase;	P31749	MAPKAPK2 \| SIK2 \| CAMKK2 \| PRKD1 \|
BAD	Bcl2-associated agonist of cell death;	Q92934	PIM1 \| PIM2 \| PIM3 \| CAMK2G \| RPS6KA2 \| RPS6KA1 \| CHEK1 \| PRKD1 \| RPS6KA3 \|
IRS1	Insulin receptor substrate 1;	P35568	Sik2 \| PIM1 \| PIM2 \| PIM3 \| SIK1 \| RPS6KA1 \| SIK2 \|
PRKD1	Serine/threonine-protein kinase D1;	Q15139	PRKD3 \| PRKD1 \|
SHC1	SHC-transforming protein 1;	P29353	Mapkapk2 \| MAPKAPK2 \|
YWHAZ	14-3-3 protein zeta/delta;	P63104	MAPKAPK2 \|