PID pathway - Class I PI3K signaling events mediated by Akt

 
 
Name Protein Names EntryName Phosphorylated by CaM kinases
AKT1 RAC-alpha serine/threonine-protein kinase; P31749 MAPKAPK2 | SIK2 | CAMKK2 | PRKD1 |
BAD Bcl2-associated agonist of cell death; Q92934 PIM1 | PIM2 | PIM3 | CAMK2G | RPS6KA2 | RPS6KA1 | CHEK1 | PRKD1 | RPS6KA3 |
BCL2L1 Bcl-2-like protein 1; Q07817 MAPKAPK2 |
CDKN1A Cyclin-dependent kinase inhibitor 1; P38936 DAPK3 | PIM2 | PIM1 | Stk11 | DAPK1 | NUAK1 |
CDKN1B Cyclin-dependent kinase inhibitor 1B; P46527 RPS6KA3 | PRKAA1 | CAMK1 | PIM1 | PIM2 | PIM3 | CAMK2A | RPS6KA2 | RPS6KA1 |
CREBBP CREB-binding protein; Q92793 CAMK4 |
EP300 Histone acetyltransferase p300; Q09472 Camk4 | CAMK4 | CAMK1 | PRKAA1 | Prkaa2 | CAMK1D | CAMK1G |
FOXO3 Forkhead box protein O3; O43524 PIM1 | PRKAA2 | PRKAA1 | MAPKAPK5 |
GSK3A Glycogen synthase kinase-3 alpha; P49840 RPS6KA3 | PRKD3 |
GSK3B Glycogen synthase kinase-3 beta; P49841 RPS6KA3 | CAMK2B | PRKD3 | RPS6KA1 | STK11 |
HSP90AA1 Heat shock protein HSP 90-alpha; P07900 PNCK |
MAP3K5 Mitogen-activated protein kinase kinase kinase 5; Q99683 PIM1 | Melk | MELK | PRKD1 | RPS6KA3 |
MDM2 E3 ubiquitin-protein ligase Mdm2; Q00987 MAPKAPK2 | PIM1 | DAPK1 | PIM2 | DAPK3 | RPS6KA1 |
RPTOR Regulatory-associated protein of mTOR; Q8N122 Prkaa1 | Prkaa2 | PRKAA1 | RPS6KA1 |
TP53 Cellular tumor antigen p53; P04637 DAPK3 | CHEK1 | STK11 | DAPK1 | MAPKAPK2 | NUAK1 | MAPKAPK5 | STK17A | CHEK2 | MELK | PRKAA1 | PRKAA2 | SIK1 |
TSC2 Tuberin; P49815 MAPKAPK2 | PIM2 | BRSK2 | RPS6KA1 |
YWHAZ 14-3-3 protein zeta/delta; P63104 MAPKAPK2 |