CaM Kinases known in this pathway:
Substrates known in this pathway:
Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
---|---|---|---|
CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha; | Q9UQM7 | CAMK2A | |
CAMK2B | Calcium/calmodulin-dependent protein kinase type II subunit beta; | Q13554 | CAMK2B | |
CAMK2D | Calcium/calmodulin-dependent protein kinase type II subunit delta; | Q13557 | CAMK2D | |
CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma; | Q13555 | CAMK2G | |
CAMK4 | Calcium/calmodulin-dependent protein kinase type IV; | Q16566 | CAMKK1 | CAMK4 | CAMK1 | |
RPS6KA1 | Ribosomal protein S6 kinase alpha-1; | Q15418 | MAPKAPK2 | RPS6KA1 | |
RPS6KA2 | Ribosomal protein S6 kinase alpha-2; | Q15349 | RPS6KA2 | |
RPS6KA3 | Ribosomal protein S6 kinase alpha-3; | P51812 | MAPKAPK2 | |
RPS6KA5 | Ribosomal protein S6 kinase alpha-5; | O75582 | RPS6KA5 | |
MAPKAPK2 | MAP kinase-activated protein kinase 2; | P49137 | MAPKAPK2 | |
RPS6KA4 | Ribosomal protein S6 kinase alpha-4; | O75676 | RPS6KA4 | |
AKT1 | RAC-alpha serine/threonine-protein kinase; | P31749 | MAPKAPK2 | SIK2 | CAMKK2 | PRKD1 | |
ATF4 | Cyclic AMP-dependent transcription factor ATF-4; | P18848 | RPS6KA3 | RPS6KA2 | |
BAD | Bcl2-associated agonist of cell death; | Q92934 | PIM1 | PIM2 | PIM3 | CAMK2G | RPS6KA2 | RPS6KA1 | CHEK1 | PRKD1 | RPS6KA3 | |
CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha; | Q9UQM7 | CAMK2A | |
CAMK2A | Calcium/calmodulin-dependent protein kinase type II subunit alpha; | Q9UQM7 | CAMK2A | |
CAMK2G | Calcium/calmodulin-dependent protein kinase type II subunit gamma; | Q13555 | CAMK2G | |
CAMK4 | Calcium/calmodulin-dependent protein kinase type IV; | Q16566 | CAMKK1 | CAMK4 | CAMK1 | |
FOXO3 | Forkhead box protein O3; | O43524 | PIM1 | PRKAA2 | PRKAA1 | MAPKAPK5 | |
GSK3B | Glycogen synthase kinase-3 beta; | P49841 | RPS6KA3 | CAMK2B | PRKD3 | RPS6KA1 | STK11 | |
IKBKB | Inhibitor of nuclear factor kappa-B kinase subunit beta; | O14920 | PRKAA2 | |
IRS1 | Insulin receptor substrate 1; | P35568 | Sik2 | PIM1 | PIM2 | PIM3 | SIK1 | RPS6KA1 | SIK2 | |
JUN | Transcription factor AP-1; | P05412 | PRKD1 | |
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5; | Q99683 | PIM1 | Melk | MELK | PRKD1 | RPS6KA3 | |
MAPKAPK2 | MAP kinase-activated protein kinase 2; | P49137 | MAPKAPK2 | |
NFKB1 | Nuclear factor NF-kappa-B p105 subunit; | P19838 | CHEK1 | |
NFKBIA | NF-kappa-B inhibitor alpha; | P25963 | RPS6KA3 | RPS6KA1 | |
NFKBIB | NF-kappa-B inhibitor beta; | Q15653 | RPS6KA1 | |
RELA | Transcription factor p65; | Q04206 | RPS6KA4 | PIM1 | CAMK2G | RPS6KA5 | CAMK4 | CHEK1 | |
RPS6KA1 | Ribosomal protein S6 kinase alpha-1; | Q15418 | MAPKAPK2 | RPS6KA1 | |
RPS6KA4 | Ribosomal protein S6 kinase alpha-4; | O75676 | RPS6KA4 | |
RPS6KA5 | Ribosomal protein S6 kinase alpha-5; | O75582 | RPS6KA5 | |
SHC1 | SHC-transforming protein 1; | P29353 | Mapkapk2 | MAPKAPK2 | |
TP53 | Cellular tumor antigen p53; | P04637 | DAPK3 | CHEK1 | STK11 | DAPK1 | MAPKAPK2 | NUAK1 | MAPKAPK5 | STK17A | CHEK2 | MELK | PRKAA1 | PRKAA2 | SIK1 | |
TP73 | Tumor protein p73; | O15350 | CHEK1 | PRKAA1 | |
YWHAZ | 14-3-3 protein zeta/delta; | P63104 | MAPKAPK2 | |