PID pathway - LPA receptor mediated events

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
PRKD1	Serine/threonine-protein kinase D1;	Q15139	TFAP2A \| COL4A3BP \| CTTN \| CREB1 \| Dlc1 \| SNAI1 \| MARK2 \| VASP \| PAK4 \| Evl \| RIN1 \| PI4KB \| Kidins220 \| SSH1 \| HSPB1 \| EGFR \| CTNNB1 \| PRKD1 \| Prkd1 \| PPP1R14A \| HDAC7 \| TLR4 \| TLR5 \| MBP \| JUN \| CACNA1C \| OSBP \| CFL1 \| Tnni3 \| Pik3r1 \| AKT1 \| Syk \| Tnni3 \| CACNA1C \| MYBPC3 \| Ahcyl1 \| MAP4K1 \| BAD \| DLC1 \| SPHK2 \| PI4KB \| HDAC5 \| PTRH2 \| PIP4K2A \| TCAP \| Prkaa1 \| DNM1L \| Prkaa2 \| Cdh2 \| RABEP1 \| REM1 \| Plekhg5 \| OSBP \| Drd1 \| Mybpc3 \| RTKN \| ARFIP1 \| ARFIP1 \| Nlrp3 \| HSPB6 \| MAP3K5 \| ITGB4 \| PLEKHG5 \| CACNA1C \| AHCYL1 \| TNNI3 \| PIK3R1 \| SYK \| TRPV1 \| HDAC7 \| RTKN \| HDAC5 \| SYK \| PRKD1 \| AHCYL1 \| KIDINS220 \| EVL \| PLCG1 variant protein \| PRKAA1 \| \| DRD1 \| MYBPC3 \|
PRKD1	Serine/threonine-protein kinase D1;	Q15139	TFAP2A \| COL4A3BP \| CTTN \| CREB1 \| Dlc1 \| SNAI1 \| MARK2 \| VASP \| PAK4 \| Evl \| RIN1 \| PI4KB \| Kidins220 \| SSH1 \| HSPB1 \| EGFR \| CTNNB1 \| PRKD1 \| Prkd1 \| PPP1R14A \| HDAC7 \| TLR4 \| TLR5 \| MBP \| JUN \| CACNA1C \| OSBP \| CFL1 \| Tnni3 \| Pik3r1 \| AKT1 \| Syk \| Tnni3 \| CACNA1C \| MYBPC3 \| Ahcyl1 \| MAP4K1 \| BAD \| DLC1 \| SPHK2 \| PI4KB \| HDAC5 \| PTRH2 \| PIP4K2A \| TCAP \| Prkaa1 \| DNM1L \| Prkaa2 \| Cdh2 \| RABEP1 \| REM1 \| Plekhg5 \| OSBP \| Drd1 \| Mybpc3 \| RTKN \| ARFIP1 \| ARFIP1 \| Nlrp3 \| HSPB6 \| MAP3K5 \| ITGB4 \| PLEKHG5 \| CACNA1C \| AHCYL1 \| TNNI3 \| PIK3R1 \| SYK \| TRPV1 \| HDAC7 \| RTKN \| HDAC5 \| SYK \| PRKD1 \| AHCYL1 \| KIDINS220 \| EVL \| PLCG1 variant protein \| PRKAA1 \| \| DRD1 \| MYBPC3 \|

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
PRKD1	Serine/threonine-protein kinase D1;	Q15139	PRKD3 \| PRKD1 \|
AKT1	RAC-alpha serine/threonine-protein kinase;	P31749	MAPKAPK2 \| SIK2 \| CAMKK2 \| PRKD1 \|
EGFR	Epidermal growth factor receptor;	P00533	PRKD1 \| CAMK2A \| PRKAA1 \|
FOS	Proto-oncogene c-Fos;	P01100	RPS6KA2 \| RPS6KA1 \|
GSK3B	Glycogen synthase kinase-3 beta;	P49841	RPS6KA3 \| CAMK2B \| PRKD3 \| RPS6KA1 \| STK11 \|
JUN	Transcription factor AP-1;	P05412	PRKD1 \|
MAPT	Microtubule-associated protein tau;	P10636	MARK1 \| MARK4 \| BRSK1 \| BRSK2 \| PRKAA1 \| SIK1 \|
NFKB1	Nuclear factor NF-kappa-B p105 subunit;	P19838	CHEK1 \|
NFKBIA	NF-kappa-B inhibitor alpha;	P25963	RPS6KA3 \| RPS6KA1 \|
PLCB3	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3;	Q01970	CAMK2A \| CAMK2B \| CAMK2D \| CAMK2G \|
PRKD1	Serine/threonine-protein kinase D1;	Q15139	PRKD3 \| PRKD1 \|
RELA	Transcription factor p65;	Q04206	RPS6KA4 \| PIM1 \| CAMK2G \| RPS6KA5 \| CAMK4 \| CHEK1 \|