CaM Kinases known in this pathway:
| Name | Synonyms | EntryName | Phosphorylate Substrates |
|---|---|---|---|
| MYLK | Myosin light chain kinase, smooth muscle; | Q15746 | MYL9 | MYL12B | CALD1 | Myl12b | MYL2 | CALD1 | MYLK | CALD1 | |
| MYLK2 | Myosin light chain kinase 2, skeletal/cardiac muscle; | Q9H1R3 | MYL9 | MYL12A | MYL12B | MEF2C | |
| MYLK3 | Myosin light chain kinase 3; | Q32MK0 | Ppp1r2 | PPP1R2B | |
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| MYLK | Myosin light chain kinase, smooth muscle; | Q15746 | MYLK | |
| MYLK2 | Myosin light chain kinase 2, skeletal/cardiac muscle; | Q9H1R3 | MAPKAPK2 | |
| ARPC5 | Actin-related protein 2/3 complex subunit 5; | O15511 | MAPKAPK2 | |
| BAIAP2 | Brain-specific angiogenesis inhibitor 1-associated protein 2; | Q9UQB8 | MARK2 | |
| CFL1 | Cofilin-1; | P23528 | HUNK | PRKD1 | |
| EGFR | Epidermal growth factor receptor; | P00533 | PRKD1 | CAMK2A | PRKAA1 | |
| ITGB1 | Integrin beta-1; | P05556 | CAMK2A | |
| ITGB4 | Integrin beta-4; | P16144 | RPS6KA1 | |
| LIMK1 | LIM domain kinase 1; | P53667 | MAPKAPK2 | CAMK4 | |
| MYL12A | Myosin regulatory light chain 12A; | P19105 | MYLK2 | DAPK1 | CAMK1 | CAMK4 | |
| MYL12B | Myosin regulatory light chain 12B; | O14950 | MYLK | DAPK1 | Dapk1 | MYLK2 | DAPK3 | |
| MYL9 | Myosin regulatory light polypeptide 9; | P24844 | MYLK | DAPK3 | Camk1 | MYLK2 | DAPK1 | DAPK2 | CAMK1 | |
| PAK1 | Serine/threonine-protein kinase PAK 1; | Q13153 | BRSK2 | STK11 | |
| PIP4K2A | Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha; | P48426 | PRKD1 | |
| PPP1R12A | Protein phosphatase 1 regulatory subunit 12A; | O14974 | NUAK1 | DAPK3 | |
| SLC9A1 | Sodium/hydrogen exchanger 1; | P19634 | RPS6KA1 | |
| SSH1 | Protein phosphatase Slingshot homolog 1; | Q8WYL5 | PRKD2 | PRKD1 | CAMK2D | |