CaMKinet | Result

Help Instruction

Double clicking on the substrate will redirect to the uniprot entry.
Clicking in the block having the substrate will zoom into its phophosites
Clicking the center of the circle will lead to zooming out.
Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
Clicking in the top right corner on the camara icon will download the image.

Sequence Logo

Graphics credits: Skylign

Substrate	Organism	PSite	Sequence(+/-7)	Conservation	Disorder	Curator Assessment	Reliability	Evidence Class	Evidence Logic	PubMed	Phospho-ELM	PhosphoSite-Plus
FOXO3 (O43524)	Homo sapiens	S253	APRRRAVSMDNSNKY	0.762	0.6906	TP	certain	experimental	72 \| 9 \|	18593906	-	In vivo
FOXO3 (O43524)	Homo sapiens	T32	QSRPRSCTWPLQRPE	0.886	0.8343	TP	certain	-	72 \| 9 \|	18593906	-	In vivo
MARK3 * (P27448-3 )	Homo sapiens	S96	KTQLNPTSLQKLFRE	0.741	0.2193	U	likely	experimental	214 \| 9 \|	15319445	-	In vitro
MARK3 * (P27448-3 )	Homo sapiens	T90	AIKIIDKTQLNPTSL	0.682	0.3019	U	likely	experimental	214 \| 9 \|	15319445	-	In vitro
MARK3 * (P27448-3 )	Homo sapiens	T95	DKTQLNPTSLQKLFR	0.017	0.3019	U	likely	experimental	214 \| 9 \|	15319445	-	In vitro
MDM2 (Q00987)	Homo sapiens	S166	SSRRRAISETEENSD	0.815	0.7718	TP	certain	experimental	72 \| 73 \| 8 \| 55 \| 107 \| 23 \|	18467333	-	In vitro and in vivo
MDM2 * (Q00987 )	Homo sapiens	S186	RQRKRHKSDSISLSF	0.958	0.6043	TP	likely	experimental	73 \| 8 \| 55 \| 107 \| 72 \| 23 \|	18467333	-	In vitro and in vivo
POU5F1 * (Q01860 )	Homo sapiens	S288	RRQKGKRSSSDYAQR	0.512	0.4409	U	likely	experimental	73 \| 214 \|	22474382	-	In vitro
POU5F1 * (Q01860 )	Homo sapiens	S289	RQKGKRSSSDYAQRE	0.382	0.5577	U	likely	experimental	73 \| 214 \|	22474382	-	In vitro
MAP3K5 (Q99683)	Homo sapiens	S83	ATRGRGSSVGGGSRR	0.816	0.6661	TP	certain	experimental	72 \| 73 \| 9 \| 55 \|	19749799	-	-
EIF4B (P23588)	Homo sapiens	S406	RPRERHPSWRSEETQ	0.581	0.8462	TP	certain	experimental	72 \| 9 \| 148 \| 28 \| 40 \| 55 \|	24777602	-	-
CDKN1A (P38936)	Homo sapiens	S146	GRKRRQTSMTDFYHS	0.575	0.7163	TP	certain	experimental	72 \| 9 \| 55 \|	17855660	-	-
FLT3 (P36888)	Homo sapiens	S935	FDSRKRPSFPNLTSF	0.457	0.0568	TP	certain	experimental	72 \| 40 \| 148 \| 9 \| 28 \|	24040307	-	-
LANA1 (Q9QR71)	Human herpesvirus 8 type P (isolate GK18)	S205	SLRKRRLSSPQGPST	-	0.892	TP	likely	experimental	72 \| 62 \|	16647097	-	-
LANA1 (Q9QR71)	Human herpesvirus 8 type P (isolate GK18)	S206	LRKRRLSSPQGPSTL	-	0.853	TP	likely	experimental	72 \| 62 \|	16647097	-	-
RELA (Q04206)	Homo sapiens	S276	SMQLRRPSDRELSEP	0.767	0.5296	TP	certain	experimental	72 \| 9 \| 55 \|	19911008	-	-
Bad (Q61337)	Mus musculus	S112	ETRSRHSSYPAGTEE	-	0.8828	TP	certain	experimental	72 \| 135 \| 133 \| 30 \| 73 \| 9 \|	16403219	-	-
Bad (Q61337)	Mus musculus	S136	PFRGRSRSAPPNLWA	-	0.6661	TP	certain	experimental	72 \| 135 \| 133 \| 30 \| 73 \| 9 \|	16403219	-	-
Bad (Q61337)	Mus musculus	S155	GRELRRMSDEFEGSF	-	0.5456	TP	certain	experimental	72 \| 135 \| 133 \| 30 \| 73 \| 9 \|	16403219	-	-
CHEK1 (O14757)	Homo sapiens	S280	AKRPRVTSGGVSESP	0.246	0.6227	TP	certain	experimental	148 \| 72 \| 73 \| 55 \| 9 \|	23748345	-	-
RUNX3 (Q13761)	Homo sapiens	S149	GRSGRGKSFTLTITV	0.497	0.3117	FP	likely	experimental	73 \| 72 \| 3 \| 31 \| 9 \| 39 \| 66 \|	18767071	-	-
HIST1H3A (P68431)	Homo sapiens	S11	TKQTARKSTGGKAPR	0.711	0.7505	TP	certain	experimental	72 \| 73 \| 55 \| 23 \| 9 \|	17643117	-	-
Myc (P01108)	Mus musculus	S329	AKRAKLDSGRVLKQI	-	0.6375	TP	certain	experimental	72 \| 62 \| 73 \| 139 \|	18438430	-	-
EIF4B (P23588)	Homo sapiens	S422	RERSRTGSESSQTGT	0.591	0.9457	TP	certain	experimental	40 \| 55 \| 9 \| 72 \| 9 \|	23749639	-	-
(Q9DUM3)	Human herpesvirus 8	S205	SLRKRRLSSPQGPST	-	0.9013	TP	certain	experimental	72 \| 73 \| 74 \| 20 \| 62 \|	19266083	-	-
(Q9DUM3)	Human herpesvirus 8	S206	LRKRRLSSPQGPSTL	-	0.8655	TP	certain	experimental	72 \| 73 \| 74 \| 20 \| 62 \|	19266083	-	-
CDKN1A * (P38936 )	Homo sapiens	T145	QGRKRRQTSMTDFYH	0.981	0.725	TP	certain	experimental	72 \| 9 \| 55 \| 73 \| 39 \|	17855660	-	-
RUNX3 (Q13761)	Homo sapiens	T151	SGRGKSFTLTITVFT	0.500	0.4369	FP	likely	experimental	73 \| 72 \| 3 \| 31 \| 9 \| 39 \| 66 \|	18767071	-	-
RUNX3 * (Q13761 )	Homo sapiens	T153	RGKSFTLTITVFTNP	0.520	0.4476	FP	likely	experimental	73 \| 72 \| 3 \| 31 \| 9 \| 39 \| 66 \|	18767071	-	-
RUNX3 (Q13761)	Homo sapiens	T155	KSFTLTITVFTNPTQ	0.518	0.4292	FP	likely	experimental	73 \| 72 \| 3 \| 31 \| 9 \| 39 \| 66 \|	18767071	-	-
CDC25A (P30304)	Homo sapiens	S116	PQKLLGCSPALKRSH	0.618	0.5456	-	-	-	-	-	Non high throughput (12411508)	-
CXCR4 (P61073)	Homo sapiens	S339	GKRGGHSSVSTESES	0.806	0.3392	-	-	-	-	-	-	In vivo
Cxcr4 (P70658)	Mus musculus	S346	GKRGGHSSVSTESES	-	0.3392	-	-	-	-	-	-	In vitro
SKP2 (Q13309)	Homo sapiens	S64	SNLGHPESPPRKRLK	0.183	0.5854	-	-	-	-	-	-	In vivo
SKP2 (Q13309)	Homo sapiens	S72	PPRKRLKSKGSDKDF	0.303	0.4801	-	-	-	-	-	-	In vivo
CDKN1B (P46527)	Homo sapiens	T157	GIRKRPATDDSSTQN	0.142	0.8198	-	-	-	-	-	-	In vitro and in vivo
CDKN1B (P46527)	Homo sapiens	T198	PGLRRRQT_______	0.507	0.9488	-	-	-	-	-	-	In vitro and in vivo
SKP2 (Q13309)	Homo sapiens	T417	WGIKCRLTLQKPSCL	0.106	0.0244	-	-	-	-	-	-	In vivo
ABCG2 (Q9UNQ0)	Homo sapiens	T362	GEKKKKITVFKEISY	0.125	0.1731	-	-	-	-	-	-	In vivo
UHRF1 (Q96T88-2)	Homo sapiens	S311	DNPMRRKSGPSCKHC	0.134	0.4766	TP	certain	experimental	73 \| 55 \| 8 \| 214 \| 23 \| 3 \| 72 \|	28394343	-	in-vitro and in-vivo
BAD (Q92934)	Homo sapiens	S75	EIRSRHSSYPAGTED	0.509	0.8198	TP	certain	experimental	73 \| 55 \|	21187157	-	in-vivo
IRS1 (P35568)	Homo sapiens	S1101	GCRRRHSSETFSSTP	0.923	0.8085	TP	certain	experimental	72 \| 140 \| 73 \| 8 \| 55 \| 148 \|	26956053	-	in-vitro and in-vivo
IRS2 (Q9Y4H2)	Homo sapiens	S1149	GGRRRHSSETFSSTT	0.742	0.9249	TP	certain	experimental	73 \| 55 \|	26956053	-	in-vitro
HBP1 (O60381)	Homo sapiens	S380	MARQRRASLSCGGPG	0.862	0.4685	TP	certain	experimental	72 \| 73 \| 23 \| 3 \| 55 \| 214 \| 8 \|	28348080	-	in-vitro and in-vivo
NKX3-1 (Q99801)	Homo sapiens	S186	TKRKQLSSELGDLEK	0.270	0.5017	TP	certain	experimental	73 \| 214 \| 72 \| 8 \|	23129228	-	in-vitro
Notch1 (Q01705)	Mus musculus	S2152	GKKARKPSTKGLACG	-	0.712	TP	certain	experimental	73 \| 8 \| 148 \| 214 \| 55 \| 72 \|	27281612	-	in-vitro and in-vivo
NKX3-1 * (Q99801 )	Homo sapiens	S195	LGDLEKHSSLPALKE	0.244	0.374	TP	likely	experimental	73 \| 214 \|	23129228	-	in-vitro
NKX3-1 * (Q99801 )	Homo sapiens	S196	GDLEKHSSLPALKEE	0.106	0.3704	TP	likely	experimental	73 \| 214 \|	23129228	-	in-vitro
AR * (P10275 )	Homo sapiens	S215	SGRAREASGAPTSSK	0.312	0.7881	TP	certain	experimental	3 \| 23 \| 73 \| 72 \| 55 \| 8 \|	22584579	-	in-vivo
HBP1 (O60381)	Homo sapiens	S372	SAVYVLSSMARQRRA	0.761	0.2752	TP	certain	experimental	72 \| 73 \| 23 \| 3 \| 55 \| 214 \| 8 \|	28348080	-	in-vitro and in-vivo
NKX3-1 (Q99801)	Homo sapiens	S185	KTKRKQLSSELGDLE	0.098	0.5098	TP	certain	experimental	73 \| 214 \| 8 \| 72 \|	23129228	-	in-vitro
FOXP3 * (Q9BZS1 )	Homo sapiens	S422	KKRSQRPSRCSNPTP	0.818	0.712	TP	certain	experimental	23 \| 53 \| 55 \| 72 \| 73 \|	25096571	-	in-vivo
AR * (P10275 )	Homo sapiens	T851	ACKRKNPTSCSRRFY	0.094	0.1137	TP	certain	experimental	3 \| 23 \| 73 \| 72 \| 55 \| 8 \|	22584579	-	in-vivo
NKX3-1 * (Q99801 )	Homo sapiens	T89	AAPEEAETLAETEPE	0.416	0.9039	TP	likely	experimental	73 \| 214 \|	23129228	-	in-vitro
PIM1 (P11309-2)	Homo sapiens	S352	FFRQRVSSECQHLIR	0.208	0.0334	-	-	-	-	-	-	-
FOXO1 (Q12778)	Homo sapiens	S256	SPRRRAASMDNNSKF	0.725	0.7163	TP	certain	predicted	14 \|	18593906	-	-
FOXO1 (Q12778)	Homo sapiens	S319	TFRPRTSSNASTISG	0.765	0.5665	TP	certain	predicted	14 \|	18593906	-	-
MYC (P01106)	Homo sapiens	S329	AKRVKLDSVRVLRQI	0.225	0.4979	TP	certain	predicted	14 \|	18438430	-	-
Myc * (P01108 )	Mus musculus	S329	AKRAKLDSGRVLKQI	-	0.6375	TP	certain	experimental	73 \| 72 \| 8 \| 55 \|	18438430	-	-
PIM1 (P11309)	Homo sapiens	S189	LKLIDFGSGALLKDT	0.122	0.0592	-	-	-	-	-	-	-
RP9 * (Q8TA86 )	Homo sapiens	S212	KKRKHKSSKSNEGSD	0.669	0.8792	-	-	-	-	-	-	-
RP9 (Q8TA86)	Homo sapiens	S214	RKHKSSKSNEGSDSE	0.270	0.8792	-	-	-	-	-	-	-
BAD (Q92934)	Homo sapiens	S118	GRELRRMSDEFVDSF	0.787	0.5758	-	-	-	-	-	-	-
BAD (Q92934)	Homo sapiens	S99	PFRGRSRSAPPNLWA	0.900	0.7982	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S75	EIRSRHSSYPAGTED	-	0.853	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S99	PFRGRSRSAPPNLWA	-	0.8343	-	-	-	-	-	-	-
(B4DZQ9)	Homo sapiens	S118	GRELRRMSDEFVDSF	-	0.6427	-	-	-	-	-	-	-
CDC25A (A0A024R2S4)	Homo sapiens	S116	PQKLLGCSPALKRSH	-	0.5456	-	-	-	-	-	-	-
NOTCH1 (P46531)	Homo sapiens	S2162	GKKVRKPSSKGLACG	0.565	0.6269	-	-	-	-	-	-	-
FOXO1 (Q12778)	Homo sapiens	T24	LPRPRSCTWPLPRPE	0.776	0.6183	TP	certain	predicted	14 \|	18593906	-	-
MARK3 * (P27448 )	Homo sapiens	T95	DKTQLNPTSLQKLFR	0.017	0.3019	FP	unlikely	experimental	73 \| 214 \|	15319445	-	-
AKT1S1 (Q96B36)	Homo sapiens	T246	LPRPRLNTSDFQKLK	0.738	0.5098	TP	certain	experimental	73 \| 36 \| 55 \| 148 \|	19276681	-	-

Help Instructions

Hovering on the "*" in "Substrate" column will display the text if there is a note by the annotator for the given site.
The column having "Sequence" motif represents phosphosite and its neighbouring 7 residues (upstream and downstream).
The score in "Conservation" column varies from 0 to 1; Higher the score more conserved is the site.
The score in "Disorder" column varies from 0 to 1; Score higher than 0.4 suggests disorder.
In the "Curator Assessment" column, TP refers to True Positive; FP refers to False Positive; and U refers to unknown if the annoatator cannot decide the status based on available information.
Hovering on the number in the "Evidence Logic" column will show the name of method used to characterize/infer the phosphosite (for more details plase follow the link)