PID pathway - Class I PI3K signaling events mediated by Akt

 
 
Name Protein Names EntryName Phosphorylated by CaM kinases
AKT1 RAC-alpha serine/threonine-protein kinase P31749 MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 |
BAD Bcl2-associated agonist of cell death Q92934 RPS6KA3 | PRKD1 | RPS6KA2 | RPS6KA1 | PIM3 | PIM1 | CAMK2G | PIM2 | CHEK1 |
BCL2L1 Bcl-2-like protein 1 Q07817 MAPKAPK2 |
CDKN1A Cyclin-dependent kinase inhibitor 1 P38936 PIM2 | PIM1 | Stk11 | DAPK3 | NUAK1 | DAPK1 |
CDKN1B Cyclin-dependent kinase inhibitor 1B P46527 RPS6KA3 | PRKAA1 | CAMK1 | PIM1 | CAMK2A | RPS6KA2 | RPS6KA1 | PIM3 | PIM2 |
CREBBP CREB-binding protein Q92793 CAMK4 |
EP300 Histone acetyltransferase p300 Q09472 CAMK1 | Camk4 | PRKAA1 | Prkaa2 | CAMK4 | CAMK1D | CAMK1G |
FOXO3 Forkhead box protein O3 O43524 PIM1 | PRKAA2 | PRKAA1 | MAPKAPK5 |
GSK3A Glycogen synthase kinase-3 alpha P49840 RPS6KA3 | PRKD3 |
GSK3B Glycogen synthase kinase-3 beta P49841 RPS6KA3 | RPS6KA1 | PRKD3 | STK11 | CAMK2B |
HSP90AA1 Heat shock protein HSP 90-alpha P07900 PNCK |
MAP3K5 Mitogen-activated protein kinase kinase kinase 5 Q99683 PIM1 | Melk | RPS6KA3 | PRKD1 | MELK |
MDM2 E3 ubiquitin-protein ligase Mdm2 Q00987 MAPKAPK2 | PIM1 | DAPK1 | DAPK3 | RPS6KA1 | PIM2 |
RPTOR Regulatory-associated protein of mTOR Q8N122 Prkaa1 | Prkaa2 | PRKAA1 | RPS6KA1 |
TP53 Cellular tumor antigen p53 P04637 DAPK1 | MAPKAPK2 | STK11 | NUAK1 | MAPKAPK5 | STK17A | CHEK1 | DAPK3 | CHEK2 | PRKAA1 | SIK1 | MELK | PRKAA2 |
TSC2 Tuberin P49815 MAPKAPK2 | PIM2 | RPS6KA1 | BRSK2 |
YWHAZ 14-3-3 protein zeta/delta P63104 MAPKAPK2 |