KEGG pathway - Bladder cancer

CaM Kinases known in this pathway:

Name	Synonyms	EntryName	Phosphorylate Substrates
DAPK1	Death-associated protein kinase 1;	P53355	TP53 \| Dapk1 \| MYL12B \| DAPK3 \| DDX58 \| TPM1 \| RPS6 \| PIN1 \| HSF1 \| MDM2 \| BECN1 \| DAPK1 \| CAMKK2 \| DAPK1 \| Stx1a \| MCM3 \| Myl12b \| RPL13A \| GRIN2B \| MYL12A \| MYL9 \| CDKN1A \| STX1A \| \|
DAPK2	Death-associated protein kinase 2;	Q9UIK4	DAPK2 \| MYL9 \| DAPK1 \| STX1A \| CAMKK2 \|
DAPK3	Death-associated protein kinase 3;	O43293	PPP1R14A \| CDKN1A \| Myl9 \| PPP1R12A \| \| TP53 \| MYL9 \| DAPK3 \| RPL13A \| MYL12B \| PPP1R12A \| HIST1H3A \| Dapk3 \| MDM2 \| Myl9 \| BECN1 \| PPP1R12A \| STAT3 \| MYL9 \| DAPK1 \| STX1A \| CAMKK2 \| PPP1R12A \|
RPS6KA5	Ribosomal protein S6 kinase alpha-5;	O75582	RELA \| HIST1H2AG \| RPS6KA5 \| Rela \| HMGN1 \| TH \| SRF \| Nr4a1 \| Creb1 \| CREB1 \| ATF1 \| ELK1 \| PLA2G4A \| HIST1H3A \| Hist1h3a \| H3F3A \| Eif4ebp1 \| Bad \| WNK1 \| Hist1h2ab \| RARA \| ATXN1 \| Trim28 \|
DAPK1	Death-associated protein kinase 1;	P53355	TP53 \| Dapk1 \| MYL12B \| DAPK3 \| DDX58 \| TPM1 \| RPS6 \| PIN1 \| HSF1 \| MDM2 \| BECN1 \| DAPK1 \| CAMKK2 \| DAPK1 \| Stx1a \| MCM3 \| Myl12b \| RPL13A \| GRIN2B \| MYL12A \| MYL9 \| CDKN1A \| STX1A \| \|
DAPK2	Death-associated protein kinase 2;	Q9UIK4	DAPK2 \| MYL9 \| DAPK1 \| STX1A \| CAMKK2 \|
DAPK3	Death-associated protein kinase 3;	O43293	PPP1R14A \| CDKN1A \| Myl9 \| PPP1R12A \| \| TP53 \| MYL9 \| DAPK3 \| RPL13A \| MYL12B \| PPP1R12A \| HIST1H3A \| Dapk3 \| MDM2 \| Myl9 \| BECN1 \| PPP1R12A \| STAT3 \| MYL9 \| DAPK1 \| STX1A \| CAMKK2 \| PPP1R12A \|
RPS6KA5	Ribosomal protein S6 kinase alpha-5;	O75582	RELA \| HIST1H2AG \| RPS6KA5 \| Rela \| HMGN1 \| TH \| SRF \| Nr4a1 \| Creb1 \| CREB1 \| ATF1 \| ELK1 \| PLA2G4A \| HIST1H3A \| Hist1h3a \| H3F3A \| Eif4ebp1 \| Bad \| WNK1 \| Hist1h2ab \| RARA \| ATXN1 \| Trim28 \|

Substrates known in this pathway:

Name	Protein Names	EntryName	Phosphorylated by CaM kinases
DAPK1	Death-associated protein kinase 1;	P53355	RPS6KA3 \| DAPK1 \| DAPK2 \| DAPK3 \| RPS6KA2 \| RPS6KA1 \| STK17A \| STK17B \|
DAPK2	Death-associated protein kinase 2;	Q9UIK4	DAPK2 \|
DAPK3	Death-associated protein kinase 3;	O43293	DAPK3 \| DAPK1 \|
RPS6KA5	Ribosomal protein S6 kinase alpha-5;	O75582	RPS6KA5 \|
CDKN1A	Cyclin-dependent kinase inhibitor 1;	P38936	DAPK3 \| PIM2 \| PIM1 \| Stk11 \| DAPK1 \| NUAK1 \|
DAPK1	Death-associated protein kinase 1;	P53355	RPS6KA3 \| DAPK1 \| DAPK2 \| DAPK3 \| RPS6KA2 \| RPS6KA1 \| STK17A \| STK17B \|
DAPK2	Death-associated protein kinase 2;	Q9UIK4	DAPK2 \|
DAPK3	Death-associated protein kinase 3;	O43293	DAPK3 \| DAPK1 \|
E2F1	Transcription factor E2F1;	Q01094	MAPKAPK2 \| CHEK2 \|
E2F3	Transcription factor E2F3;	O00716	CHEK1 \| CHEK2 \|
EGFR	Epidermal growth factor receptor;	P00533	PRKD1 \| CAMK2A \| PRKAA1 \|
ERBB2	Receptor tyrosine-protein kinase erbB-2;	P04626	CAMK2A \| PRKAA1 \|
MDM2	E3 ubiquitin-protein ligase Mdm2;	Q00987	MAPKAPK2 \| PIM1 \| DAPK1 \| PIM2 \| DAPK3 \| RPS6KA1 \|
RB1	Retinoblastoma-associated protein;	P06400	CHEK1 \| CHEK2 \|
RPS6KA5	Ribosomal protein S6 kinase alpha-5;	O75582	RPS6KA5 \|
TP53	Cellular tumor antigen p53;	P04637	DAPK3 \| CHEK1 \| STK11 \| DAPK1 \| MAPKAPK2 \| NUAK1 \| MAPKAPK5 \| STK17A \| CHEK2 \| MELK \| PRKAA1 \| PRKAA2 \| SIK1 \|