PRKD1 | Serine/threonine-protein kinase D1

 

Help Instruction

  • Double clicking on the substrate will redirect to the uniprot entry.
  • Clicking in the block having the substrate will zoom into its phophosites
  • Clicking the center of the circle will lead to zooming out.
  • Clicking on the phosphosite will render the phosphosite in its 3D structure (if structure information/mapping is available).
  • The color of every substrate has ben kept different in the Sunburst diagram for visual clarity.
  • Clicking in the top right corner on the camara icon will download the image.
 
Substrate Organism PSite Sequence(+/-7) Conservation Disorder Curator Assessment Reliability Evidence Class Evidence Logic PubMed Phospho-ELM PhosphoSite-Plus
TFAP2A (P05549) Homo sapiens S258 GVLRRAKSKNGGRSL 0.747 0.4292 TP certain experimental 72 | 9 | 55 | 74 | 18845787 - -
TFAP2A (P05549) Homo sapiens S326 EFLNRQHSDPNEQVT 0.153 0.5758 TP certain experimental 72 | 9 | 55 | 74 | 18845787 - -
COL4A3BP (Q9Y5P4) Homo sapiens S132 SSLRRHGSMVSLVSG 0.931 0.4441 TP certain experimental 62 | 55 | 72 | 73 | 17591919 - -
CTTN (Q14247) Homo sapiens S298 EKLAKHESQQDYSKG 0.484 0.5456 TP certain experimental 72 | 73 | 55 | 9 | 20363754 - -
CREB1 (P16220) Homo sapiens S98 KDLKRLFSGTQISTI - 0.4186 TP certain experimental 62 | 72 | 55 | 17389598 - -
CREB1 (P16220) Homo sapiens S133 EILSRRPSYRKILND - 0.4979 TP certain experimental 62 | 72 | 55 | 73 | 23 | 17389598 - -
Dlc1 (Q63744) Rattus norvegicus S807 NTLKRENSSPRVMQR - 0.5055 TP certain experimental 55 | 30 | 72 | 148 | 9 | 21087603 - -
SNAI1 (O95863) Homo sapiens S11 SFLVRKPSDPNRKPN 0.356 0.6948 TP certain experimental 66 | 72 | 73 | 8 | 55 | 20940406 - -
MARK2 (Q7KZI7) Homo sapiens S400 HKVQRSVSANPKQRR 0.995 0.8279 TP certain experimental 73 | 9 | 55 | 107 | 72 | 19011111 - -
VASP (P50552) Homo sapiens S157 EHIERRVSNAGGPPA 0.401 0.9473 TP certain experimental 72 | 147 | 9 | 55 | 73 | 16 | 23846685 - -
VASP (P50552) Homo sapiens S322 TTLPRMKSSSSVTTS 0.364 0.8596 TP certain experimental 72 | 9 | 55 | 73 | 148 | 16 | 23846685 - -
PAK4 (O96013) Homo sapiens S99 MSVTRSNSLRRDSPP 0.968 0.892 TP certain experimental 72 | 55 | 9 | 73 | 39 | 23841590 - -
PAK4 (O96013) Homo sapiens S474 KEVPRRKSLVGTPYW 0.786 0.2951 TP certain experimental 72 | 55 | 73 | 148 | 21832093 - -
Evl (P70429) Mus musculus S343 SLLSRTPSVAKSPEA - 0.8421 TP certain experimental 72 | 73 | 9 | 55 | 40 | 23 | 19000756 - -
RIN1 (Q13671) Homo sapiens S292 QLLRRESSVGYRVPA 0.737 0.5456 TP certain experimental 55 | 62 | 73 | 30 | 72 | 148 | 39 | 21209314 - -
RIN1 (Q13671) Homo sapiens S351 RPLLRSMSAAFCSLL 0.732 0.391 TP certain experimental 72 | 9 | 30 | 55 | 21209314 - -
PI4KB (Q9UBF8) Homo sapiens S294 SNLKRTASNPKVENE 0.332 0.7459 TP certain experimental 72 | 9 | 55 | 73 | 74 | 16100512 - -
Kidins220 (Q9EQG6) Rattus norvegicus S918 RTITRQMSFDLTKLL - 0.2752 TP certain experimental 23 | 72 | 73 | 9 | 55 | 131 | 10998417 - -
SSH1 (Q8WYL5) Homo sapiens S978 SPLKRSHSLAKLGSL 0.802 0.4369 TP certain experimental 72 | 73 | 55 | 9 | 143 | 19329994 - -
HSPB1 (P04792) Homo sapiens S82 RALSRQLSSGVSEIR 0.622 0.374 TP certain experimental 55 | 72 | 9 | 73 | 15728188 - -
EGFR (P00533) Homo sapiens T678 RHIVRKRTLRRLLQE 0.415 0.3182 TP certain experimental 72 | 9 | 10523301 - -
EGFR (P00533) Homo sapiens T693 RELVEPLTPSGEAPN 0.275 0.4476 TP certain experimental 72 | 9 | 10523301 - -
CTNNB1 (P35222) Homo sapiens T112 EGMQIPSTQFDAAHP 0.535 0.6375 TP certain experimental 66 | 72 | 135 | 62 | 23 | 73 | 147 | 19141652 - -
CTNNB1 (P35222) Homo sapiens T120 QFDAAHPTNVQRLAE 0.721 0.7755 TP certain experimental 66 | 72 | 135 | 62 | 23 | 73 | 147 | 19141652 - -
PRKD1 (Q15139) Homo sapiens S205 GVRRRRLSNVSLTGV 0.511 0.2328 - - - - - Non high throughput (10867018) -
Prkd1 (Q62101) Mus musculus S203 GVRRRRLSNVSLTGL - 0.2258 - - - - - Non high throughput (10867018) -
PPP1R14A (Q96A00) Homo sapiens T38 QKRHARVTVKYDRRE 0.852 0.4979 - - - - - Non high throughput (15003508) In vitro
Prkd1 (Q62101) Mus musculus S916 KALSERVSIL_____ - 0.2258 - - - - - Non high throughput (10473617, 10867018) -
PRKD1 (Q15139) Homo sapiens S910 KALGERVSIL_____ 0.500 0.2849 - - - - - Non high throughput (10473617, 14607845, 16563698) In vitro and in vivo
Prkd1 (Q62101) Mus musculus S748 GEKSFRRSVVGTPAY - 0.1323 - - - - - Non high throughput (10867018, 12407104) -
Prkd1 (Q62101) Mus musculus S744 ARIIGEKSFRRSVVG - 0.0817 - - - - - Non high throughput (10867018, 2407104) -
HDAC7 (Q8WUI4) Homo sapiens S155 FPLRKTVSEPNLKLR 0.972 0.6227 - - - - - Non high throughput (15623513, 18509061, 18617643) In vivo
TLR4 (O00206) Homo sapiens S790 VELYRLLSRNTYLEW 0.047 0.0543 - - - - - - In vitro
TLR5 (O60602) Homo sapiens S805 YQLMKHQSIRGFVQK 0.044 0.1007 - - - - - - In vitro and in vivo
MBP (P02686-5) Homo sapiens S162 FKLGGRDSRSGSPMA 0.116 0.7036 - - - - - - In vitro
JUN (P05412) Homo sapiens S63 KNSDLLTSPDVGLLK 0.767 0.3426 - - - - - - In vitro
CACNA1C (P15381) Oryctolagus cuniculus S1928 ASLGRRASFHLECLK - 0.3392 - - - - - - In vitro
OSBP (P22059) Homo sapiens S240 TALQRSLSELESLKL 0.351 0.4652 - - - - - - In vivo
CFL1 (P23528) Homo sapiens S3 _____MASGVAVSDG 0.971 0.1611 - - - - - - In vivo
Tnni3 (P23693) Rattus norvegicus S23 PAPVRRRSSANYRAY - 0.6755 - - - - - - In vitro
Tnni3 (P23693) Rattus norvegicus S24 APVRRRSSANYRAYA - 0.708 - - - - - - In vitro
Pik3r1 (P26450) Mus musculus S652 TFLVRESSKQGCYAC - 0.2002 - - - - - - In vitro and in vivo
AKT1 (P31749) Homo sapiens S473 RPHFPQFSYSASGTA 0.952 0.5342 - - - - - - In vivo
Syk (P48025) Mus musculus S291 ISRIKSYSFPKPGHK - 0.4292 - - - - - - In vitro
Tnni3 (P48787) Mus musculus S23 PAPVRRRSSANYRAY - 0.6906 - - - - - - In vitro
Tnni3 (P48787) Mus musculus S24 APVRRRSSANYRAYA - 0.7163 - - - - - - In vitro
CACNA1C (Q13936) Homo sapiens S1981 ASLGRRASFHLECLK 0.889 0.384 - - - - - - In vivo
CTTN (Q14247) Homo sapiens S348 EAVTSKTSNIRANFE 0.455 0.5382 - - - - - - In vitro and in vivo
MYBPC3 (Q14896) Homo sapiens S304 SLLKKRDSFRTPRDS 0.236 0.3704 - - - - - - In vitro
PRKD1 (Q15139) Homo sapiens S742 GEKSFRRSVVGTPAY 0.714 0.1323 - - - - - - In vivo
Ahcyl1 (Q80SW1) Mus musculus S68 RSLSRSISQSSTDSY - 0.5854 - - - - - - In vitro
HDAC7 (Q8WUI4) Homo sapiens S358 WPLSRTRSEPLPPSA 0.984 0.8013 - - - - - - In vivo
HDAC7 (Q8WUI4) Homo sapiens S486 RPLSRAQSSPAAPAS 0.983 0.805 - - - - - - In vivo
SSH1 (Q8WYL5) Homo sapiens S402 MGVSRSASTVIAYAM 0.666 0.1611 - - - - - - In vitro
SSH1 (Q8WYL5) Homo sapiens S937 SNLTRSSSSDSIHSV 0.839 0.6948 - - - - - - In vitro and in vivo
MAP4K1 (Q92918) Homo sapiens S171 ATLARRLSFIGTPYW 0.778 0.0454 - - - - - - In vitro
BAD (Q92934) Homo sapiens S118 GRELRRMSDEFVDSF 0.787 0.5758 - - - - - - In vitro and in vivo
BAD (Q92934) Homo sapiens S75 EIRSRHSSYPAGTED 0.509 0.8198 - - - - - - In vitro and in vivo
BAD (Q92934) Homo sapiens S99 PFRGRSRSAPPNLWA 0.900 0.7982 - - - - - - In vitro
DLC1 (Q96QB1) Homo sapiens S1244 NTLKRENSSPRVMQR 0.595 0.4979 - - - - - - In vitro and in vivo
SPHK2 (Q9NRA0) Homo sapiens S419 AHSPLHRSVSDLPLP 0.402 0.6712 - - - - - - In vivo
SPHK2 (Q9NRA0) Homo sapiens S421 SPLHRSVSDLPLPLP 0.657 0.5992 - - - - - - In vivo
PI4KB (Q9UBF8-2) Homo sapiens S294 SNLKRTASNPKVENE 0.332 0.7547 - - - - - - In vitro and in vivo
HDAC5 (Q9UQL6) Homo sapiens S259 FPLRKTASEPNLKVR 0.835 0.6712 - - - - - - In vivo
HDAC5 (Q9UQL6) Homo sapiens S498 RPLSRTQSSPLPQSP 0.940 0.9126 - - - - - - In vitro and in vivo
PTRH2 (Q9Y3E5) Homo sapiens S5 ___MPSKSLVMEYLA 0.304 0.2645 - - - - - - In vivo
PTRH2 (Q9Y3E5) Homo sapiens S87 GKVAAQCSHAAVSAY 0.357 0.1702 - - - - - - In vitro and in vivo
AKT1 (P31749) Homo sapiens T308 KDGATMKTFCGTPEY 0.710 0.2645 - - - - - - In vivo
PIP4K2A (P48426) Homo sapiens T376 KAAHAAKTVKHGAGA 0.780 0.5176 - - - - - - In vitro and in vivo
TCAP (O15273) Homo sapiens S157 GALRRSLSRSMSQEA 0.250 0.6806 - - - - - - in-vitro
Prkaa1 (Q5EG47) Mus musculus S494 GTATPQRSGSISNYR - 0.5533 - - - - - - in-vivo
DNM1L (O00429) Homo sapiens S637 VPVARKLSAREQRDC 0.300 0.4119 - - - - - - in-vitro
Prkaa2 (Q8BRK8) Mus musculus S491 STPQRSCSAAGLHRA - 0.5419 - - - - - - in-vivo
Cdh2 (Q9Z1Y3) Rattus norvegicus S869 GSGSTAGSLSSLNSS - 0.7331 - - - - - - in-vivo
RABEP1 (Q15276) Homo sapiens S407 DGLRRAQSTDSLGTS 0.942 0.5342 - - - - - - in-vitro
REM1 (O75628) Homo sapiens S18 TPLHRRASTPLPLSP 0.999 0.8681 - - - - - - in-vivo
Plekhg5 (Q66T02) Mus musculus S92 SVLARNVSTRSCPPR - 0.6991 - - - - - - in-vivo
Plekhg5 (Q66T02) Mus musculus S806 PTILRKSSNSLDSEH - 0.5665 - - - - - - in-vivo
OSBP (P16258) Oryctolagus cuniculus S242 TALQRSLSELESLKL - 0.4582 - - - - - - in-vivo
Cdh2 (Q9Z1Y3) Rattus norvegicus S871 GSTAGSLSSLNSSSS - 0.8125 - - - - - - in-vivo
Drd1 (P18901) Rattus norvegicus S421 EKLSPALSVILDYDT - 0.2064 - - - - - - in-vivo
Mybpc3 (O70468) Mus musculus S302 SLLKKRDSFRRDSKL - 0.384 - - - - - - in-vivo
RTKN (Q9BST9-2) Homo sapiens S435 QALAKQGSLYHEMAI 0.149 0.4979 - - - - - - in-vivo
ARFIP1 (P53367) Homo sapiens S132 LELVRKWSLNTYKCT 0.753 0.1914 - - - - - - in-vitro and in-vivo
Cdh2 (Q9Z1Y3) Rattus norvegicus S872 STAGSLSSLNSSSSG - 0.8125 - - - - - - in-vivo
ARFIP1 (P53367-2) Homo sapiens S100 LELVRKWSLNTYKCT 0.588 0.2034 - - - - - - in-vivo
Nlrp3 (Q8R4B8) Mus musculus S291 CKILRKPSRILFLMD - 0.0433 - - - - - - in-vivo
HSPB6 (O14558) Homo sapiens S16 PSWLRRASAPLPGLS 0.206 0.4409 - - - - - - in-vitro and in-vivo
TCAP (O15273) Homo sapiens S161 RSLSRSMSQEAQRG_ 0.844 0.5665 - - - - - - in-vitro
MAP3K5 (Q99683) Homo sapiens T838 GINPCTETFTGTLQY 0.596 0.2328 - - - - - - in-vivo
ITGB4 (P16144-2) Homo sapiens T1736 EFVSRTLTTSGTLST 0.859 0.4864 - - - - - - in-vitro
PLEKHG5 (O94827-7) Homo sapiens S92 SVLARNVSTRSCPPR 0.764 0.7289 - - - - - - -
CACNA1C (Q13936-9) Homo sapiens S1898 LLRKANPSRCHSRES 0.720 0.4801 - - - - - - -
AHCYL1 (O43865) Homo sapiens S68 RSLSRSISQSSTDSY 0.608 0.5854 - - - - - - -
TNNI3 (P19429) Homo sapiens S23 PAPIRRRSSNYRAYA 0.104 0.6906 - - - - - - -
TNNI3 (P19429) Homo sapiens S24 APIRRRSSNYRAYAT 0.016 0.7163 - - - - - - -
PIK3R1 (P27986) Homo sapiens S652 TFLVRESSKQGCYAC 0.443 0.2002 - - - - - - -
SYK (P43405) Homo sapiens S291 WSAGGIISRIKSYSF 0.497 0.3053 - - - - - - -
PRKD1 (Q15139) Homo sapiens S738 ARIIGEKSFRRSVVG 0.590 0.0817 - - - - - - -
TRPV1 (Q8NER1) Homo sapiens S117 LRLYDRRSIFEAVAQ 0.045 0.3019 - - - - - - -
HDAC7 (Q8WUI4-5) Homo sapiens S194 FPLRKTVSEPNLKLR 0.194 0.6227 - - - - - - -
HDAC7 (Q8WUI4-5) Homo sapiens S220 NPLLRKESAPPSLRR 0.385 0.8343 - - - - - - -
HDAC7 (Q8WUI4-5) Homo sapiens S397 WPLSRTRSEPLPPSA 0.646 0.8013 - - - - - - -
RTKN (Q9BST9) Homo sapiens S448 QALAKQGSLYHEMAI 0.952 0.4979 - - - - - - -
HDAC5 (Q9UQL6-3) Homo sapiens S260 FPLRKTASEPNLKVR 0.838 0.6712 - - - - - - -
HDAC5 (Q9UQL6-3) Homo sapiens S499 RPLSRTQSSPLPQSP 0.120 0.9126 - - - - - - -
SYK (A0A024R244) Homo sapiens S297 ISRIKSYSFPKPGHR - 0.4186 - - - - - - -
PRKD1 (F8WBA3) Homo sapiens S205 GVRRRRLSNVSLTGV - 0.2399 - - - - - - -
PRKD1 (F8WBA3) Homo sapiens S746 ARIIGEKSFRRSVVG - 0.0817 - - - - - - -
PRKD1 (F8WBA3) Homo sapiens S750 GEKSFRRSVVGTPAY - 0.1323 - - - - - - -
PRKD1 (F8WBA3) Homo sapiens S918 KALGERVSIL_____ - 0.2849 - - - - - - -
AHCYL1 (A0A024R0A8) Homo sapiens S68 RSLSRSISQSSTDSY - 0.5854 - - - - - - -
KIDINS220 (Q9ULH0) Homo sapiens S918 RTITRQMSFDLTKLL 0.187 0.268 - - - - - - -
DLC1 (Q96QB1) Homo sapiens S733 VPMVRKRSVSNSTQT 0.731 0.662 - - - - - - -
EVL (Q9UI08) Homo sapiens S345 SILSRTPSVAKSPEA 0.770 0.8235 - - - - - - -
PLCG1 variant protein (Q4LE43) Homo sapiens S1370 HGRAREGSFESRYQQ - 0.384 - - - - - - -
PRKAA1 (Q13131) Homo sapiens S494 GTATPQRSGSVSNYR 0.112 0.5758 - - - - - - -
(B2RA25) Homo sapiens S491 STPQRSCSAAGLHRP - 0.6531 - - - - - - -
DRD1 (P21728) Homo sapiens S421 EKLSPALSVILDYDT 0.623 0.2164 - - - - - - -
MYBPC3 (A8MXZ9) Homo sapiens S304 SLLKKSSSFRTPRDS - 0.3631 - - - - - - -
CACNA1C (Q13936) Homo sapiens T1928 EVKMNHDTEACSEPS 0.098 0.5456 - - - - - - -

Help Instructions