CaM Kinases known in this pathway:
| Name | Synonyms | EntryName | Phosphorylate Substrates |
|---|---|---|---|
| PIM1 | Serine/threonine-protein kinase pim-1 | P11309 | FOXO3 | MARK3 | MDM2 | POU5F1 | MAP3K5 | EIF4B | CDKN1A | FLT3 | LANA1 | RELA | Bad | CHEK1 | RUNX3 | HIST1H3A; HIST1H3B; HIST1H3C; HIST1H3D; HIST1H3E; HIST1H3F; HIST1H3G; HIST1H3H; HIST1H3I; HIST1H3J | Myc | | CDC25A | CXCR4 | Cxcr4 | SKP2 | CDKN1B | ABCG2 | NKX3-1 | UHRF1 | BAD | IRS1 | IRS2 | HBP1 | Notch1 | AR | FOXP3 | PIM1 | FOXO1 | MYC | PIM1 | RP9 | | CDC25A | NOTCH1 | MARK3 | AKT1S1 | |
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 | MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 | |
| BCL2L1 | Bcl-2-like protein 1 | Q07817 | MAPKAPK2 | |
| CREBBP | CREB-binding protein | Q92793 | CAMK4 | |
| EP300 | Histone acetyltransferase p300 | Q09472 | CAMK1 | Camk4 | PRKAA1 | Prkaa2 | CAMK4 | CAMK1D | CAMK1G | |
| SPRY2 | Protein sprouty homolog 2 | O43597 | MKNK2 | MKNK1 | |
| STAT3 | Signal transducer and activator of transcription 3 | P40763 | RPS6KA3 | CAMK2G | Dapk3 | DAPK3 | |