CaM Kinases known in this pathway:
| Name | Synonyms | EntryName | Phosphorylate Substrates |
|---|---|---|---|
| PRKD1 | Serine/threonine-protein kinase D1 | Q15139 | TFAP2A | COL4A3BP | CTTN | CREB1 | Dlc1 | SNAI1 | MARK2 | VASP | PAK4 | Evl | RIN1 | PI4KB | Kidins220 | SSH1 | HSPB1 | EGFR | CTNNB1 | TLR4 | TLR5 | MBP | JUN | CACNA1C | OSBP | CFL1 | Tnni3 | Pik3r1 | AKT1 | Syk | Tnni3 | CACNA1C | MYBPC3 | PRKD1 | Prkd1 | Ahcyl1 | HDAC7 | MAP4K1 | BAD | DLC1 | SPHK2 | PI4KB | HDAC5 | PTRH2 | PIP4K2A | PPP1R14A | TCAP | Prkaa1 | DNM1L | Prkaa2 | Cdh2 | RABEP1 | REM1 | Plekhg5 | OSBP | Drd1 | Mybpc3 | RTKN | ARFIP1 | ARFIP1 | Nlrp3 | HSPB6 | MAP3K5 | ITGB4 | PLEKHG5 | CACNA1C | AHCYL1 | TNNI3 | PIK3R1 | SYK | TRPV1 | HDAC7 | RTKN | HDAC5 | SYK | PRKD1 | AHCYL1 | KIDINS220 | EVL | PLCG1 variant protein | PRKAA1 | | DRD1 | MYBPC3 | |
Substrates known in this pathway:
| Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
|---|---|---|---|
| AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 | MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 | |
| EGFR | Epidermal growth factor receptor | P00533 | PRKD1 | CAMK2A | PRKAA1 | |
| FOS | Proto-oncogene c-Fos | P01100 | RPS6KA2 | RPS6KA1 | |
| GSK3B | Glycogen synthase kinase-3 beta | P49841 | RPS6KA3 | RPS6KA1 | PRKD3 | STK11 | CAMK2B | |
| JUN | Transcription factor AP-1 | P05412 | PRKD1 | |
| MAPT | Microtubule-associated protein tau | P10636 | SIK1 | PRKAA1 | BRSK2 | BRSK1 | MARK4 | MARK1 | |
| NFKB1 | Nuclear factor NF-kappa-B p105 subunit | P19838 | CHEK1 | |
| NFKBIA | NF-kappa-B inhibitor alpha | P25963 | RPS6KA3 | RPS6KA1 | |
| PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3 | Q01970 | CAMK2A | CAMK2B | CAMK2D | CAMK2G | |
| PRKD1 | Serine/threonine-protein kinase D1 | Q15139 | PRKD3 | PRKD1 | |
| RELA | Transcription factor p65 | Q04206 | PIM1 | CAMK2G | RPS6KA4 | RPS6KA5 | CAMK4 | CHEK1 | |