CaM Kinases known in this pathway:
Name | Synonyms | EntryName | Phosphorylate Substrates |
---|---|---|---|
MAPKAPK2 | MAP kinase-activated protein kinase 2 | P49137 | TH | EEF2K | TP53 | KRT18 | TH | TH | VIM | SRF | Hspb1 | Lsp1 | Zfp36 | LSP1 | Ddit3 | VIM | MAPKAPK2 | MDM2 | RCSD1 | Hnrnpa0 | Krt20 | HSPB1 | TSC2 | BAG2 | ALOX5 | YWHAZ | ARPC5 | CDC25B | HSF1 | LIMK1 | AKT1 | PLK1 | ZFP36L1 | Etv1 | RTN4 | TRIM29 | PIAS1 | AATF | AGO2 | PARN | CRYAB | Creb1 | CREB1 | Rps6ka1 | ATF1 | SHC1 | CDC25B | CDC25C | KRT20 | Pde4a | Creb1 | BCL2L1 | HNRNPA0 | Lpcat2 | Gys1 | Rps6ka3 | WNK4 | Rbm7 | MRTFA | Ripk1 | TH | Mrtfa | CEP131 | DDX5 | DAZL | RIPK1 | Hif3a | TRIM28 | PFKFB3 | BECN1 | ZFP36 | PDE4A | LSP1 | ETV1 | RPS6KA3 | E2F1 | RPS6KA1 | LPCAT2 | TAB3 | MYLK2 | RPS6KA1 | ZFP36 | DDIT3 | | | RBM7 | RIPK1 | PDE4A | |
MAPKAPK3 | MAP kinase-activated protein kinase 3 | Q16644 | RCSD1 | TCF3 | RTN4 | RTN4 | BECN1 | EEF2K | HSPB1 | KRT20 | TAB3 | |
Substrates known in this pathway:
Name | Protein Names | EntryName | Phosphorylated by CaM kinases |
---|---|---|---|
AKT1 | RAC-alpha serine/threonine-protein kinase | P31749 | MAPKAPK2 | SIK2 | PRKD1 | CAMKK2 | |
BAD | Bcl2-associated agonist of cell death | Q92934 | RPS6KA3 | PRKD1 | RPS6KA2 | RPS6KA1 | PIM3 | PIM1 | CAMK2G | PIM2 | CHEK1 | |
HSPB1 | Heat shock protein beta-1 | P04792 | MAPKAPK2 | PRKD1 | MAPKAPK5 | MAPKAPK3 | CAMK1 | CAMK4 | |
MAPKAPK2 | MAP kinase-activated protein kinase 2 | P49137 | MAPKAPK2 | |
NFATC4 | Nuclear factor of activated T-cells, cytoplasmic 4 | Q14934 | RPS6KA3 | RPS6KA2 | |
NOS3 | Nitric oxide synthase, endothelial | P29474 | PRKAA1 | Prkaa2 | Prkaa1 | PRKAA2 | |
PLA2G4A | Cytosolic phospholipase A2 | P47712 | RPS6KA5 | MAPKAPK5 | CAMK2A | MKNK1 | |
SPHK2 | Sphingosine kinase 2 | Q9NRA0 | PRKD1 | PRKD3 | |